KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS11
All Species:
20
Human Site:
S112
Identified Species:
40
UniProt:
Q6UWP2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWP2
NP_077284.2
260
28308
S112
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
Chimpanzee
Pan troglodytes
XP_511425
274
29730
S126
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
Rhesus Macaque
Macaca mulatta
XP_001111397
255
27833
S107
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
Dog
Lupus familis
XP_548249
274
29660
S126
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3U0B3
260
28256
S112
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
Rat
Rattus norvegicus
Q5M875
300
33476
E135
D
L
L
S
T
K
D
E
E
I
T
K
T
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q71R50
255
27708
E107
P
L
L
S
G
K
T
E
G
W
R
T
M
I
D
Frog
Xenopus laevis
NP_001088432
181
19907
I39
T
E
G
W
K
T
M
I
D
V
N
V
L
A
L
Zebra Danio
Brachydanio rerio
NP_001093518
258
28208
D110
P
L
L
S
G
R
T
D
G
W
R
N
M
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780227
255
28419
E106
S
L
L
D
G
T
P
E
E
W
Q
K
S
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P33207
319
33530
S176
L
L
I
R
M
K
Q
S
Q
W
D
E
V
I
A
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
D110
A
G
K
A
L
G
S
D
R
V
G
Q
I
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
97.3
89
N.A.
92.6
21.6
N.A.
N.A.
78.8
54.2
73
N.A.
N.A.
N.A.
N.A.
46.9
Protein Similarity:
100
82.1
97.3
91.6
N.A.
96.1
39
N.A.
N.A.
89.2
61.9
86.1
N.A.
N.A.
N.A.
N.A.
65.7
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
53.3
6.6
53.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
66.6
20
73.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
49.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
0
0
0
0
0
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
9
17
9
0
9
42
0
0
25
% D
% Glu:
0
9
0
0
0
0
0
25
17
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% F
% Gly:
0
9
9
0
67
9
0
0
59
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
9
0
0
9
25
0
% I
% Lys:
0
0
9
0
9
25
0
0
0
0
42
17
0
0
0
% K
% Leu:
9
84
75
0
9
0
0
0
0
0
0
0
9
9
9
% L
% Met:
0
0
0
0
9
0
9
0
0
0
0
0
59
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
42
% N
% Pro:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
9
0
9
9
0
0
0
% Q
% Arg:
0
0
0
9
0
9
0
0
9
0
17
0
0
0
0
% R
% Ser:
9
0
0
67
0
42
9
50
0
0
0
0
9
0
0
% S
% Thr:
50
0
0
0
9
17
59
0
0
0
9
9
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
17
0
9
9
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
75
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _