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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FIP1L1
All Species:
23.94
Human Site:
S548
Identified Species:
65.83
UniProt:
Q6UN15
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UN15
NP_001128409.1
594
66526
S548
H
K
S
S
R
S
N
S
R
R
R
H
E
S
E
Chimpanzee
Pan troglodytes
XP_001147016
603
67380
S557
H
K
S
S
R
S
N
S
R
R
R
H
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001090808
594
66538
S548
H
K
S
S
R
S
N
S
R
R
R
H
E
S
E
Dog
Lupus familis
XP_853955
764
84414
S718
H
K
S
S
R
S
N
S
R
R
R
H
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D824
581
64940
S535
H
K
S
S
R
S
N
S
R
R
R
H
E
S
E
Rat
Rattus norvegicus
Q5U317
536
60169
R491
K
S
S
R
S
N
S
R
R
R
H
E
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517022
711
77022
P655
H
P
S
L
P
F
P
P
P
P
R
R
S
P
P
Chicken
Gallus gallus
XP_001233386
773
84522
S727
H
K
S
S
R
S
N
S
R
R
R
H
D
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5XJD3
570
62947
S521
K
E
E
G
R
H
K
S
S
R
S
S
S
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.8
73.5
N.A.
93.5
87.7
N.A.
26.5
62.7
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
99.8
75.9
N.A.
94.4
88.3
N.A.
37.1
68.5
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
20
93.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
20
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
12
12
0
0
0
0
0
0
0
0
12
56
12
78
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
78
0
0
0
0
12
0
0
0
0
12
67
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
23
67
0
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
67
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
12
0
12
12
12
12
0
0
0
12
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
78
0
0
12
78
89
78
12
0
12
12
% R
% Ser:
0
12
89
67
12
67
12
78
12
0
12
12
34
67
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _