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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM111B
All Species:
9.09
Human Site:
T591
Identified Species:
33.33
UniProt:
Q6SJ93
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6SJ93
NP_001136175.1
734
84674
T591
I
K
K
I
D
G
C
T
V
I
P
L
N
E
R
Chimpanzee
Pan troglodytes
XP_508447
704
81156
T561
I
K
K
I
D
G
C
T
V
I
P
L
N
E
R
Rhesus Macaque
Macaca mulatta
XP_001091252
732
84404
T589
I
K
K
I
D
G
C
T
V
I
P
L
N
E
R
Dog
Lupus familis
XP_852339
735
84785
A592
V
K
K
I
D
G
C
A
V
I
P
I
N
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2L9
613
69930
E474
I
Y
I
I
G
H
P
E
G
E
K
K
S
I
D
Rat
Rattus norvegicus
NP_001102633
610
69271
H471
G
L
I
Y
L
I
G
H
P
D
G
E
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923070
538
61425
A399
G
G
N
K
K
M
D
A
C
F
I
I
A
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
90.5
61.6
N.A.
32.8
32.4
N.A.
N.A.
N.A.
N.A.
22
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.3
94.4
77.6
N.A.
50.6
50.8
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
29
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
58
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
58
0
15
0
0
15
0
0
0
0
29
% D
% Glu:
0
0
0
0
0
0
0
15
0
15
0
15
0
43
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
29
15
0
0
15
58
15
0
15
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% H
% Ile:
58
0
29
72
0
15
0
0
0
58
15
29
0
15
0
% I
% Lys:
0
58
58
15
15
0
0
0
0
0
15
15
15
29
0
% K
% Leu:
0
15
0
0
15
0
0
0
0
0
0
43
0
0
0
% L
% Met:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
0
0
0
58
0
0
% N
% Pro:
0
0
0
0
0
0
15
0
15
0
58
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
15
% S
% Thr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
15
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
15
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _