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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR74 All Species: 21.52
Human Site: Y210 Identified Species: 47.33
UniProt: Q6RFH5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6RFH5 NP_060563.2 385 42441 Y210 G Y H Q V R V Y D P A S P Q R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116087 385 42512 Y210 G Y H Q V R V Y D P A S P Q R
Dog Lupus familis XP_540899 383 42161 Y211 G Y H Q V R V Y D P A S P Q R
Cat Felis silvestris
Mouse Mus musculus Q8VCG3 384 42618 Y210 G Y H Q V R V Y D P V S P Q R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521546 212 23396 D63 D L R V P I W D Q D I Q F D A
Chicken Gallus gallus
Frog Xenopus laevis NP_001091349 376 41912 Y203 S H H Q V R V Y D P S S P Q R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_506824 431 48512 L195 T K L H E M R L Y D P R A Q R
Sea Urchin Strong. purpuratus XP_791892 394 44687 Y209 G H C Q V R L Y D P S A T Q R
Poplar Tree Populus trichocarpa XP_002318118 355 38740 W185 L E N S T K I W T A K P P P K
Maize Zea mays NP_001140808 475 51504 L241 T N S H Q V R L Y D T A L Q R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_174226 468 52252 L242 T K S H Q V R L Y D I S T Q R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.6 90.3 N.A. 89.3 N.A. N.A. 26.7 N.A. 54 N.A. N.A. N.A. N.A. 31.5 42.6
Protein Similarity: 100 N.A. 98.6 92.9 N.A. 93.5 N.A. N.A. 34 N.A. 69 N.A. N.A. N.A. N.A. 48.2 64.7
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 0 N.A. 80 N.A. N.A. N.A. N.A. 13.3 60
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 0 N.A. 93.3 N.A. N.A. N.A. N.A. 13.3 86.6
Percent
Protein Identity: 28 26.1 N.A. 27.3 N.A. N.A.
Protein Similarity: 43.6 40.8 N.A. 41.4 N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. 20 N.A. N.A.
P-Site Similarity: 40 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 28 19 10 0 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 10 55 37 0 0 0 10 0 % D
% Glu: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 19 46 28 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 0 0 0 19 0 0 0 0 % I
% Lys: 0 19 0 0 0 10 0 0 0 0 10 0 0 0 10 % K
% Leu: 10 10 10 0 0 0 10 28 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 55 10 10 55 10 0 % P
% Gln: 0 0 0 55 19 0 0 0 10 0 0 10 0 82 0 % Q
% Arg: 0 0 10 0 0 55 28 0 0 0 0 10 0 0 82 % R
% Ser: 10 0 19 10 0 0 0 0 0 0 19 55 0 0 0 % S
% Thr: 28 0 0 0 10 0 0 0 10 0 10 0 19 0 0 % T
% Val: 0 0 0 10 55 19 46 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % W
% Tyr: 0 37 0 0 0 0 0 55 28 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _