KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR74
All Species:
13.64
Human Site:
Y204
Identified Species:
30
UniProt:
Q6RFH5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6RFH5
NP_060563.2
385
42441
Y204
K
L
V
T
C
T
G
Y
H
Q
V
R
V
Y
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116087
385
42512
Y204
K
L
V
T
C
T
G
Y
H
Q
V
R
V
Y
D
Dog
Lupus familis
XP_540899
383
42161
Y205
K
L
V
T
C
T
G
Y
H
Q
V
R
V
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCG3
384
42618
Y204
K
L
V
T
C
T
G
Y
H
Q
V
R
V
Y
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521546
212
23396
L57
V
R
N
D
W
L
D
L
R
V
P
I
W
D
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091349
376
41912
H197
K
I
V
T
C
T
S
H
H
Q
V
R
V
Y
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_506824
431
48512
K189
N
T
I
L
E
A
T
K
L
H
E
M
R
L
Y
Sea Urchin
Strong. purpuratus
XP_791892
394
44687
H203
K
V
V
T
C
T
G
H
C
Q
V
R
L
Y
D
Poplar Tree
Populus trichocarpa
XP_002318118
355
38740
E179
E
V
N
L
W
D
L
E
N
S
T
K
I
W
T
Maize
Zea mays
NP_001140808
475
51504
N235
R
K
I
V
A
C
T
N
S
H
Q
V
R
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174226
468
52252
K236
R
K
F
V
T
G
T
K
S
H
Q
V
R
L
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
90.3
N.A.
89.3
N.A.
N.A.
26.7
N.A.
54
N.A.
N.A.
N.A.
N.A.
31.5
42.6
Protein Similarity:
100
N.A.
98.6
92.9
N.A.
93.5
N.A.
N.A.
34
N.A.
69
N.A.
N.A.
N.A.
N.A.
48.2
64.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
6.6
93.3
Percent
Protein Identity:
28
26.1
N.A.
27.3
N.A.
N.A.
Protein Similarity:
43.6
40.8
N.A.
41.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
40
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
55
10
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
10
0
0
0
0
0
0
10
55
% D
% Glu:
10
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
46
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
46
28
0
0
0
0
0
% H
% Ile:
0
10
19
0
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
55
19
0
0
0
0
0
19
0
0
0
10
0
0
0
% K
% Leu:
0
37
0
19
0
10
10
10
10
0
0
0
10
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
19
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
55
19
0
0
0
10
% Q
% Arg:
19
10
0
0
0
0
0
0
10
0
0
55
28
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
19
10
0
0
0
0
0
% S
% Thr:
0
10
0
55
10
55
28
0
0
0
10
0
0
0
10
% T
% Val:
10
19
55
19
0
0
0
0
0
10
55
19
46
0
0
% V
% Trp:
0
0
0
0
19
0
0
0
0
0
0
0
10
10
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
55
28
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _