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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR74
All Species:
14.24
Human Site:
T343
Identified Species:
31.33
UniProt:
Q6RFH5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6RFH5
NP_060563.2
385
42441
T343
N
K
V
P
L
E
D
T
E
T
D
E
L
W
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116087
385
42512
T343
N
K
V
P
L
E
D
T
E
T
D
E
L
W
A
Dog
Lupus familis
XP_540899
383
42161
T341
K
K
A
P
P
E
D
T
E
T
D
E
L
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCG3
384
42618
T343
N
Q
V
P
S
E
D
T
E
T
D
E
L
W
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521546
212
23396
Q171
E
A
D
G
S
H
E
Q
E
A
E
Q
G
R
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091349
376
41912
Q328
D
A
T
S
P
A
E
Q
D
V
K
E
E
E
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_506824
431
48512
I351
D
E
D
D
D
D
V
I
E
E
D
D
V
W
G
Sea Urchin
Strong. purpuratus
XP_791892
394
44687
T339
S
K
K
G
K
K
K
T
A
Q
E
E
G
D
E
Poplar Tree
Populus trichocarpa
XP_002318118
355
38740
L308
P
V
I
A
S
C
G
L
D
S
Y
L
R
L
W
Maize
Zea mays
NP_001140808
475
51504
K433
A
R
K
E
K
K
K
K
K
S
R
G
I
E
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174226
468
52252
K426
E
K
A
P
V
K
T
K
K
S
K
K
E
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
90.3
N.A.
89.3
N.A.
N.A.
26.7
N.A.
54
N.A.
N.A.
N.A.
N.A.
31.5
42.6
Protein Similarity:
100
N.A.
98.6
92.9
N.A.
93.5
N.A.
N.A.
34
N.A.
69
N.A.
N.A.
N.A.
N.A.
48.2
64.7
P-Site Identity:
100
N.A.
100
80
N.A.
86.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
100
N.A.
100
80
N.A.
93.3
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
53.3
40
Percent
Protein Identity:
28
26.1
N.A.
27.3
N.A.
N.A.
Protein Similarity:
43.6
40.8
N.A.
41.4
N.A.
N.A.
P-Site Identity:
0
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
33.3
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
19
10
0
10
0
0
10
10
0
0
0
0
37
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
19
10
10
10
37
0
19
0
46
10
0
10
10
% D
% Glu:
19
10
0
10
0
37
19
0
55
10
19
55
19
19
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
19
0
0
10
0
0
0
0
10
19
0
19
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
10
46
19
0
19
28
19
19
19
0
19
10
0
10
0
% K
% Leu:
0
0
0
0
19
0
0
10
0
0
0
10
37
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
46
19
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
19
0
10
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
0
10
10
19
% R
% Ser:
10
0
0
10
28
0
0
0
0
28
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
10
46
0
37
0
0
0
0
0
% T
% Val:
0
10
28
0
10
0
10
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _