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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR74
All Species:
22.73
Human Site:
S320
Identified Species:
50
UniProt:
Q6RFH5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6RFH5
NP_060563.2
385
42441
S320
Q
L
N
C
L
L
L
S
G
R
D
N
W
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116087
385
42512
S320
Q
L
N
C
L
L
L
S
G
R
D
N
W
E
D
Dog
Lupus familis
XP_540899
383
42161
S321
Q
L
N
C
L
L
L
S
G
R
D
N
W
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCG3
384
42618
S320
Q
L
N
C
L
L
L
S
G
R
D
N
W
E
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521546
212
23396
L156
G
G
R
E
P
P
A
L
T
G
P
L
V
P
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091349
376
41912
T312
Q
L
N
C
L
L
L
T
S
R
E
K
W
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_506824
431
48512
R305
R
L
N
R
V
L
L
R
D
N
L
S
I
L
N
Sea Urchin
Strong. purpuratus
XP_791892
394
44687
S318
K
L
N
C
L
L
F
S
S
R
D
F
T
Q
D
Poplar Tree
Populus trichocarpa
XP_002318118
355
38740
S293
K
C
S
G
S
I
R
S
I
A
R
H
P
E
L
Maize
Zea mays
NP_001140808
475
51504
D351
H
L
T
T
V
V
L
D
S
H
F
S
V
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174226
468
52252
D352
H
L
T
G
L
V
F
D
S
G
F
S
G
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
90.3
N.A.
89.3
N.A.
N.A.
26.7
N.A.
54
N.A.
N.A.
N.A.
N.A.
31.5
42.6
Protein Similarity:
100
N.A.
98.6
92.9
N.A.
93.5
N.A.
N.A.
34
N.A.
69
N.A.
N.A.
N.A.
N.A.
48.2
64.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
26.6
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
28
26.1
N.A.
27.3
N.A.
N.A.
Protein Similarity:
43.6
40.8
N.A.
41.4
N.A.
N.A.
P-Site Identity:
13.3
20
N.A.
20
N.A.
N.A.
P-Site Similarity:
40
46.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
10
0
55
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
10
0
46
0
0
0
46
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
0
73
28
% E
% Phe:
0
0
0
0
0
0
19
0
0
0
19
10
0
0
0
% F
% Gly:
10
10
0
19
0
0
0
0
37
19
0
0
10
0
0
% G
% His:
19
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
0
0
0
10
0
0
% I
% Lys:
19
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
82
0
0
64
64
64
10
0
0
10
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
64
0
0
0
0
0
0
10
0
37
0
0
10
% N
% Pro:
0
0
0
0
10
10
0
0
0
0
10
0
10
10
0
% P
% Gln:
46
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
10
10
0
0
10
10
0
55
10
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
55
37
0
0
28
0
0
0
% S
% Thr:
0
0
19
10
0
0
0
10
10
0
0
0
10
0
10
% T
% Val:
0
0
0
0
19
19
0
0
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _