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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR74
All Species:
16.67
Human Site:
S121
Identified Species:
36.67
UniProt:
Q6RFH5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6RFH5
NP_060563.2
385
42441
S121
D
K
D
K
D
T
S
S
D
P
L
L
E
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116087
385
42512
S121
D
N
D
K
N
T
S
S
D
P
L
L
E
L
R
Dog
Lupus familis
XP_540899
383
42161
S122
E
N
D
K
E
A
S
S
D
P
L
L
E
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCG3
384
42618
S121
E
N
D
K
E
A
S
S
D
P
L
L
E
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521546
212
23396
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091349
376
41912
E119
A
G
D
S
D
N
L
E
V
Q
V
G
A
G
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_506824
431
48512
E114
D
K
S
E
I
L
S
E
W
K
T
G
P
G
V
Sea Urchin
Strong. purpuratus
XP_791892
394
44687
T124
K
G
K
P
E
H
I
T
E
I
K
A
G
A
N
Poplar Tree
Populus trichocarpa
XP_002318118
355
38740
S109
R
R
E
R
S
S
G
S
C
T
L
L
T
C
T
Maize
Zea mays
NP_001140808
475
51504
S147
I
T
K
E
N
A
A
S
G
S
H
I
E
P
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174226
468
52252
G147
V
K
F
P
D
A
H
G
N
S
T
D
D
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
90.3
N.A.
89.3
N.A.
N.A.
26.7
N.A.
54
N.A.
N.A.
N.A.
N.A.
31.5
42.6
Protein Similarity:
100
N.A.
98.6
92.9
N.A.
93.5
N.A.
N.A.
34
N.A.
69
N.A.
N.A.
N.A.
N.A.
48.2
64.7
P-Site Identity:
100
N.A.
86.6
66.6
N.A.
66.6
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
N.A.
93.3
80
N.A.
86.6
N.A.
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
28
26.1
N.A.
27.3
N.A.
N.A.
Protein Similarity:
43.6
40.8
N.A.
41.4
N.A.
N.A.
P-Site Identity:
20
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
46.6
40
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
37
10
0
0
0
0
10
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
28
0
46
0
28
0
0
0
37
0
0
10
10
0
0
% D
% Glu:
19
0
10
19
28
0
0
19
10
0
0
0
46
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
0
0
10
10
10
0
0
19
10
19
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
10
0
0
10
0
10
0
0
10
% I
% Lys:
10
28
19
37
0
0
0
0
0
10
10
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
10
0
0
0
46
46
0
37
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
28
0
0
19
10
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
19
0
0
0
0
0
37
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
19
% R
% Ser:
0
0
10
10
10
10
46
55
0
19
0
0
0
0
28
% S
% Thr:
0
10
0
0
0
19
0
10
0
10
19
0
10
0
10
% T
% Val:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _