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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC23A3
All Species:
3.94
Human Site:
S253
Identified Species:
9.63
UniProt:
Q6PIS1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PIS1
NP_001138361.1
610
64531
S253
P
W
R
R
A
S
T
S
S
T
H
T
P
L
P
Chimpanzee
Pan troglodytes
XP_516102
493
52279
S172
V
S
G
A
V
V
V
S
G
L
L
Q
G
T
M
Rhesus Macaque
Macaca mulatta
XP_001097078
493
52279
S172
V
S
G
A
V
V
V
S
G
L
L
Q
G
T
M
Dog
Lupus familis
XP_545654
603
63331
T252
A
S
N
S
S
P
H
T
P
I
P
V
F
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60850
611
64860
T256
C
S
W
R
P
S
S
T
S
T
H
I
C
I
P
Rat
Rattus norvegicus
Q9WTW8
647
70051
W300
I
Y
K
S
K
K
G
W
T
A
Y
K
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426596
574
60155
V252
W
S
W
L
L
G
V
V
V
G
E
W
P
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339365
609
66281
K276
A
Y
K
D
K
K
W
K
V
F
Q
Y
P
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185517
690
74101
V341
S
Q
K
K
L
R
L
V
R
M
Y
I
F
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93039
526
57799
H205
I
L
S
Q
Y
L
P
H
L
F
K
C
K
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
75
79.5
N.A.
78
27
N.A.
N.A.
45.4
N.A.
32.4
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
78
77.3
85
N.A.
84.9
47.9
N.A.
N.A.
55.5
N.A.
51.3
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
6.6
6.6
0
N.A.
40
0
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
6.6
13.3
N.A.
60
26.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
20
10
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
20
0
0
20
0
10
% F
% Gly:
0
0
20
0
0
10
10
0
20
10
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
20
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
0
0
0
10
0
20
0
10
0
% I
% Lys:
0
0
30
10
20
20
0
10
0
0
10
10
10
0
0
% K
% Leu:
0
10
0
10
20
10
10
0
10
20
20
0
10
30
40
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
20
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
10
10
0
10
0
10
0
30
0
20
% P
% Gln:
0
10
0
10
0
0
0
0
0
0
10
20
0
10
0
% Q
% Arg:
0
0
10
20
0
10
0
0
10
0
0
0
0
30
0
% R
% Ser:
10
50
10
20
10
20
10
30
20
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
20
10
20
0
10
0
20
0
% T
% Val:
20
0
0
0
20
20
30
20
20
0
0
10
0
0
0
% V
% Trp:
10
10
20
0
0
0
10
10
0
0
0
10
0
0
0
% W
% Tyr:
0
20
0
0
10
0
0
0
0
0
20
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _