KinATLAS
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DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INO80C
All Species:
31.52
Human Site:
S175
Identified Species:
49.52
UniProt:
Q6PI98
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PI98
NP_919257.2
192
20643
S175
S
Y
I
R
R
L
P
S
D
V
V
T
G
Y
L
Chimpanzee
Pan troglodytes
XP_001135553
210
22556
S193
S
Y
I
R
R
L
P
S
D
V
V
T
G
Y
L
Rhesus Macaque
Macaca mulatta
XP_001104744
192
20647
S175
S
Y
I
R
R
L
P
S
D
V
V
T
G
Y
L
Dog
Lupus familis
XP_547606
246
26199
S229
S
Y
I
R
R
L
P
S
D
V
V
T
G
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHA0
191
20387
S174
S
Y
I
R
R
L
P
S
D
V
V
T
G
Y
L
Rat
Rattus norvegicus
Q5BJY3
191
20406
S174
S
Y
I
R
R
L
P
S
D
V
V
T
G
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513039
175
19236
D159
Y
I
R
M
L
P
S
D
V
V
T
G
Y
L
A
Chicken
Gallus gallus
XP_419041
185
19512
S168
A
Y
I
R
M
L
P
S
D
V
V
T
G
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002108
210
22453
T193
S
Y
I
R
Q
L
P
T
D
V
V
T
G
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727280
110
12413
D94
S
M
Q
H
M
P
S
D
I
V
N
G
Y
L
M
Honey Bee
Apis mellifera
XP_624857
271
31350
M254
A
T
V
R
S
L
P
M
D
I
T
A
G
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785838
291
30508
Q274
A
Q
L
R
M
F
P
Q
D
I
V
N
G
L
L
Poplar Tree
Populus trichocarpa
XP_002323030
123
14393
E107
L
V
R
S
L
P
N
E
H
V
Q
R
Y
L
A
Maize
Zea mays
NP_001147223
125
14698
E109
Q
I
R
M
L
P
D
E
Y
V
Q
R
Y
L
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32617
166
18514
G150
I
V
K
P
M
A
P
G
V
D
Q
E
Y
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
98.4
74.3
N.A.
90.6
91.1
N.A.
65
73.4
N.A.
53.8
N.A.
28.1
29.8
N.A.
35.7
Protein Similarity:
100
91.4
99.4
75.6
N.A.
95.3
94.7
N.A.
72.9
81.2
N.A.
67.6
N.A.
42.1
43.9
N.A.
45.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
86.6
N.A.
86.6
N.A.
13.3
46.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
N.A.
100
N.A.
20
66.6
N.A.
60
Percent
Protein Identity:
25.5
27.6
N.A.
N.A.
23.9
N.A.
Protein Similarity:
41.6
39.5
N.A.
N.A.
40.6
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
6.6
6.6
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
7
0
0
0
0
0
7
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
14
67
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
14
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
14
67
0
0
% G
% His:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
14
54
0
0
0
0
0
7
14
0
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
7
0
7
0
20
60
0
0
0
0
0
0
0
40
67
% L
% Met:
0
7
0
14
27
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
7
0
0
0
% N
% Pro:
0
0
0
7
0
27
74
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
7
0
7
0
0
7
0
0
20
0
0
0
0
% Q
% Arg:
0
0
20
67
40
0
0
0
0
0
0
14
0
0
0
% R
% Ser:
54
0
0
7
7
0
14
47
0
0
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
7
0
0
14
54
0
0
0
% T
% Val:
0
14
7
0
0
0
0
0
14
80
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
54
0
0
0
0
0
0
7
0
0
0
34
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _