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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFWD3
All Species:
15.45
Human Site:
Y567
Identified Species:
48.57
UniProt:
Q6PCD5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PCD5
NP_060594.3
774
85094
Y567
A
N
G
S
I
L
V
Y
D
V
R
N
T
S
S
Chimpanzee
Pan troglodytes
XP_001137255
774
85068
Y567
A
N
G
S
I
L
V
Y
D
V
R
N
T
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853024
773
85269
Y566
V
N
G
S
I
L
L
Y
D
L
R
N
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIK8
774
84294
Y567
A
S
G
S
I
L
I
Y
D
L
R
N
T
N
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514261
744
80102
S543
V
Y
D
L
R
D
T
S
S
H
V
Q
E
L
V
Chicken
Gallus gallus
XP_414051
670
73089
H469
D
L
R
D
T
N
S
H
V
Q
E
L
V
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393432
491
55412
S290
V
H
A
Y
Q
T
E
S
P
L
W
S
C
C
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326378
681
75875
T480
E
S
R
L
G
H
T
T
D
P
I
H
T
V
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
77.1
N.A.
68.2
N.A.
N.A.
57.3
53.2
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
86.3
N.A.
79
N.A.
N.A.
70
65.2
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
66.6
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
24
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% C
% Asp:
13
0
13
13
0
13
0
0
63
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
0
0
13
0
0
0
13
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
0
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
0
13
0
13
0
13
0
13
0
0
0
% H
% Ile:
0
0
0
0
50
0
13
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
25
0
50
13
0
0
38
0
13
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
38
0
0
0
13
0
0
0
0
0
50
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
13
13
0
0
0
13
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
13
0
13
0
0
25
% Q
% Arg:
0
0
25
0
13
0
0
0
0
0
50
0
0
0
0
% R
% Ser:
0
25
0
50
0
0
13
25
13
0
0
13
0
38
38
% S
% Thr:
0
0
0
0
13
13
25
13
0
0
0
0
63
0
13
% T
% Val:
38
0
0
0
0
0
25
0
13
25
13
0
13
13
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
13
% W
% Tyr:
0
13
0
13
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _