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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFWD3
All Species:
10
Human Site:
S216
Identified Species:
31.43
UniProt:
Q6PCD5
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PCD5
NP_060594.3
774
85094
S216
Q
V
S
S
S
S
D
S
D
S
D
S
S
A
E
Chimpanzee
Pan troglodytes
XP_001137255
774
85068
S216
Q
V
S
S
S
S
D
S
D
S
D
S
S
A
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853024
773
85269
S217
Q
V
S
S
S
S
N
S
D
S
D
S
S
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIK8
774
84294
P217
H
D
S
E
T
R
N
P
P
S
G
T
D
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514261
744
80102
P196
Q
Q
Q
P
P
L
P
P
T
P
T
R
L
G
A
Chicken
Gallus gallus
XP_414051
670
73089
S122
R
Q
P
R
V
G
G
S
Q
R
T
V
S
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393432
491
55412
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326378
681
75875
R133
V
E
E
E
R
N
K
R
R
R
V
E
K
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
77.1
N.A.
68.2
N.A.
N.A.
57.3
53.2
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
86.3
N.A.
79
N.A.
N.A.
70
65.2
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
13.3
N.A.
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
46.6
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
24
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
25
0
38
0
38
0
13
0
13
% D
% Glu:
0
13
13
25
0
0
0
0
0
0
0
13
0
0
38
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
13
0
0
0
13
0
0
13
13
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
0
% K
% Leu:
0
0
0
0
0
13
0
0
0
0
0
0
13
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
25
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
13
13
0
13
25
13
13
0
0
0
0
0
% P
% Gln:
50
25
13
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
13
0
0
13
13
13
0
13
13
25
0
13
0
0
13
% R
% Ser:
0
0
50
38
38
38
0
50
0
50
0
38
50
13
0
% S
% Thr:
0
0
0
0
13
0
0
0
13
0
25
13
0
13
0
% T
% Val:
13
38
0
0
13
0
0
0
0
0
13
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _