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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A4
All Species:
21.82
Human Site:
S478
Identified Species:
43.64
UniProt:
Q6P5W5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5W5
NP_060237.2
647
68392
S478
A
D
L
V
A
E
E
S
P
E
L
L
N
P
E
Chimpanzee
Pan troglodytes
XP_001157597
650
68681
S480
A
D
L
V
A
E
E
S
P
E
L
L
N
P
E
Rhesus Macaque
Macaca mulatta
XP_001098635
661
69564
S492
A
D
L
V
A
E
E
S
P
E
L
L
K
P
E
Dog
Lupus familis
XP_539217
650
69535
S481
A
D
L
V
A
E
E
S
P
E
L
L
S
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q78IQ7
660
71045
T491
S
D
L
V
A
E
E
T
P
E
L
L
N
P
E
Rat
Rattus norvegicus
A0JPN2
656
71103
T487
S
D
L
V
T
E
E
T
P
E
L
L
N
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
D498
E
D
S
E
P
V
R
D
S
A
D
S
L
T
A
Chicken
Gallus gallus
Q5ZI20
366
39255
I231
L
N
L
L
A
N
T
I
D
N
F
T
H
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
H669
G
H
G
H
G
H
S
H
H
G
H
C
H
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
G525
E
H
E
S
S
H
H
G
H
S
H
R
H
G
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
P868
F
E
T
E
T
P
L
P
T
E
D
T
D
C
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
H334
N
L
F
S
D
G
V
H
N
F
T
D
G
M
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
93
74
N.A.
71
71.6
N.A.
31.4
22.4
N.A.
26.5
N.A.
21.2
N.A.
N.A.
21.4
Protein Similarity:
100
98.9
95.1
80.7
N.A.
79.6
80.3
N.A.
48.8
35.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
33
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
73.3
N.A.
6.6
13.3
N.A.
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
93.3
N.A.
6.6
33.3
N.A.
13.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
50
0
0
0
0
9
0
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
9
% C
% Asp:
0
59
0
0
9
0
0
9
9
0
17
9
9
0
17
% D
% Glu:
17
9
9
17
0
50
50
0
0
59
0
0
0
0
42
% E
% Phe:
9
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% F
% Gly:
9
0
9
0
9
9
0
9
0
9
0
0
9
17
0
% G
% His:
0
17
0
9
0
17
9
17
17
0
17
0
25
0
9
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
9
59
9
0
0
9
0
0
0
50
50
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
9
0
0
0
9
0
0
9
9
0
0
34
0
0
% N
% Pro:
0
0
0
0
9
9
0
9
50
0
0
0
0
42
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% R
% Ser:
17
0
9
17
9
0
9
34
9
9
0
9
9
9
0
% S
% Thr:
0
0
9
0
17
0
9
17
9
0
9
17
0
9
0
% T
% Val:
0
0
0
50
0
9
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _