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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A4
All Species:
21.82
Human Site:
S457
Identified Species:
43.64
UniProt:
Q6P5W5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5W5
NP_060237.2
647
68392
S457
V
S
L
Q
L
A
P
S
E
L
R
Q
P
K
P
Chimpanzee
Pan troglodytes
XP_001157597
650
68681
S459
V
S
L
Q
L
A
P
S
E
L
R
Q
P
K
P
Rhesus Macaque
Macaca mulatta
XP_001098635
661
69564
S471
V
S
L
Q
L
A
P
S
E
L
R
Q
P
K
P
Dog
Lupus familis
XP_539217
650
69535
S460
V
S
L
Q
L
A
P
S
E
L
R
P
P
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q78IQ7
660
71045
S470
I
S
L
Q
L
A
P
S
N
L
R
Q
S
K
Q
Rat
Rattus norvegicus
A0JPN2
656
71103
S466
I
S
L
Q
L
S
P
S
N
L
R
Q
S
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
C477
G
F
F
L
I
E
K
C
F
V
L
L
M
P
E
Chicken
Gallus gallus
Q5ZI20
366
39255
Q210
Q
C
N
G
S
S
L
Q
S
C
R
T
D
N
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
A648
E
E
D
N
V
P
K
A
K
S
K
K
H
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
D504
Y
A
V
N
K
A
K
D
K
D
S
R
N
D
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
S847
G
K
N
G
L
S
L
S
E
S
K
S
E
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
Q313
G
K
S
D
K
P
E
Q
V
E
T
R
S
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
93
74
N.A.
71
71.6
N.A.
31.4
22.4
N.A.
26.5
N.A.
21.2
N.A.
N.A.
21.4
Protein Similarity:
100
98.9
95.1
80.7
N.A.
79.6
80.3
N.A.
48.8
35.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
33
P-Site Identity:
100
100
100
86.6
N.A.
73.3
66.6
N.A.
0
6.6
N.A.
0
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
13.3
13.3
N.A.
33.3
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
50
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
9
0
9
0
0
9
9
0
% D
% Glu:
9
9
0
0
0
9
9
0
42
9
0
0
9
0
9
% E
% Phe:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
25
0
0
17
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
17
% H
% Ile:
17
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
17
0
25
0
17
0
17
9
0
50
0
% K
% Leu:
0
0
50
9
59
0
17
0
0
50
9
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
17
17
0
0
0
0
17
0
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
17
50
0
0
0
0
9
34
9
25
% P
% Gln:
9
0
0
50
0
0
0
17
0
0
0
42
0
0
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
59
17
0
0
9
% R
% Ser:
0
50
9
0
9
25
0
59
9
17
9
9
25
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% T
% Val:
34
0
9
0
9
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _