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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A4
All Species:
11.52
Human Site:
S439
Identified Species:
23.03
UniProt:
Q6P5W5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5W5
NP_060237.2
647
68392
S439
E
D
G
P
C
G
H
S
S
H
S
H
G
G
H
Chimpanzee
Pan troglodytes
XP_001157597
650
68681
S441
E
D
G
P
C
G
H
S
S
H
S
H
G
G
H
Rhesus Macaque
Macaca mulatta
XP_001098635
661
69564
S453
E
D
G
P
C
G
H
S
S
H
S
H
G
G
H
Dog
Lupus familis
XP_539217
650
69535
C442
E
D
S
K
D
G
P
C
S
H
S
H
G
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q78IQ7
660
71045
G452
D
Q
D
S
E
K
D
G
P
C
S
H
G
G
H
Rat
Rattus norvegicus
A0JPN2
656
71103
G448
D
Q
D
H
E
K
D
G
P
C
S
H
G
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
W459
H
E
G
K
E
Y
I
W
K
L
L
G
V
I
G
Chicken
Gallus gallus
Q5ZI20
366
39255
G192
Y
P
P
S
K
V
A
G
K
S
Q
R
A
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
S630
M
P
L
N
I
S
D
S
D
H
P
Y
E
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
T486
H
E
G
Q
D
S
N
T
I
V
T
D
L
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
R829
T
A
N
G
Q
R
G
R
A
M
S
G
Q
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
K295
S
A
S
D
A
T
D
K
S
D
S
G
T
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
93
74
N.A.
71
71.6
N.A.
31.4
22.4
N.A.
26.5
N.A.
21.2
N.A.
N.A.
21.4
Protein Similarity:
100
98.9
95.1
80.7
N.A.
79.6
80.3
N.A.
48.8
35.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
33
P-Site Identity:
100
100
100
66.6
N.A.
33.3
33.3
N.A.
6.6
0
N.A.
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
40
40
N.A.
13.3
0
N.A.
20
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
9
0
9
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
25
0
0
9
0
17
0
0
0
0
0
% C
% Asp:
17
34
17
9
17
0
34
0
9
9
0
9
0
9
0
% D
% Glu:
34
17
0
0
25
0
0
0
0
0
0
0
9
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
42
9
0
34
9
25
0
0
0
25
50
59
17
% G
% His:
17
0
0
9
0
0
25
0
0
42
0
50
0
0
50
% H
% Ile:
0
0
0
0
9
0
9
0
9
0
0
0
0
9
9
% I
% Lys:
0
0
0
17
9
17
0
9
17
0
0
0
0
0
9
% K
% Leu:
0
0
9
0
0
0
0
0
0
9
9
0
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
9
25
0
0
9
0
17
0
9
0
0
0
9
% P
% Gln:
0
17
0
9
9
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
0
0
0
9
0
9
0
0
0
9
0
0
0
% R
% Ser:
9
0
17
17
0
17
0
34
42
9
67
0
0
0
9
% S
% Thr:
9
0
0
0
0
9
0
9
0
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _