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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A4
All Species:
23.03
Human Site:
S306
Identified Species:
46.06
UniProt:
Q6P5W5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5W5
NP_060237.2
647
68392
S306
A
L
L
Q
Q
Q
L
S
G
A
C
T
S
Q
S
Chimpanzee
Pan troglodytes
XP_001157597
650
68681
S308
A
L
L
Q
Q
Q
L
S
G
A
C
T
S
Q
S
Rhesus Macaque
Macaca mulatta
XP_001098635
661
69564
S320
A
L
L
Q
Q
Q
L
S
G
A
C
T
S
Q
P
Dog
Lupus familis
XP_539217
650
69535
S312
A
L
L
Q
Q
Q
L
S
G
A
C
N
P
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q78IQ7
660
71045
S316
A
L
V
Q
Q
Q
L
S
G
A
C
S
P
Y
P
Rat
Rattus norvegicus
A0JPN2
656
71103
S313
A
L
V
Q
Q
Q
L
S
E
A
C
S
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
Q337
E
I
F
L
P
A
S
Q
G
S
I
S
K
E
N
Chicken
Gallus gallus
Q5ZI20
366
39255
I72
F
M
V
G
L
S
G
I
F
P
L
L
V
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
F421
L
Y
Q
I
D
R
R
F
C
I
L
H
Y
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
K355
T
M
I
S
E
W
R
K
S
V
E
K
K
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
S275
S
L
V
Q
Q
I
L
S
G
A
C
E
I
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
N175
G
G
G
H
S
H
S
N
D
H
H
E
N
H
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
93
74
N.A.
71
71.6
N.A.
31.4
22.4
N.A.
26.5
N.A.
21.2
N.A.
N.A.
21.4
Protein Similarity:
100
98.9
95.1
80.7
N.A.
79.6
80.3
N.A.
48.8
35.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
33
P-Site Identity:
100
100
93.3
80
N.A.
66.6
66.6
N.A.
6.6
0
N.A.
0
N.A.
0
N.A.
N.A.
53.3
P-Site Similarity:
100
100
93.3
80
N.A.
80
80
N.A.
40
13.3
N.A.
6.6
N.A.
33.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
9
0
0
0
59
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
59
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
9
% D
% Glu:
9
0
0
0
9
0
0
0
9
0
9
17
0
17
0
% E
% Phe:
9
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% F
% Gly:
9
9
9
9
0
0
9
0
59
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
9
0
0
0
9
9
9
0
17
9
% H
% Ile:
0
9
9
9
0
9
0
9
0
9
9
0
9
9
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
9
17
0
0
% K
% Leu:
9
59
34
9
9
0
59
0
0
0
17
9
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
9
9
0
9
% N
% Pro:
0
0
0
0
9
0
0
0
0
9
0
0
17
0
42
% P
% Gln:
0
0
9
59
59
50
0
9
0
0
0
0
0
34
0
% Q
% Arg:
0
0
0
0
0
9
17
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
9
9
9
17
59
9
9
0
25
34
9
17
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
25
0
9
17
% T
% Val:
0
0
34
0
0
0
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _