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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A4
All Species:
15.45
Human Site:
S258
Identified Species:
30.91
UniProt:
Q6P5W5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5W5
NP_060237.2
647
68392
S258
R
D
P
V
P
L
I
S
S
S
N
S
S
S
V
Chimpanzee
Pan troglodytes
XP_001157597
650
68681
S260
Q
D
P
V
P
L
I
S
S
N
N
S
S
S
V
Rhesus Macaque
Macaca mulatta
XP_001098635
661
69564
T272
Q
D
P
V
P
L
V
T
S
N
D
S
S
S
V
Dog
Lupus familis
XP_539217
650
69535
T264
Q
G
P
V
P
L
T
T
L
N
S
S
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q78IQ7
660
71045
P268
Q
D
S
E
L
H
T
P
H
N
S
N
S
S
V
Rat
Rattus norvegicus
A0JPN2
656
71103
T265
Q
D
S
E
L
H
A
T
H
N
S
S
S
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
G289
R
K
K
K
L
I
V
G
R
E
C
A
Y
L
L
Chicken
Gallus gallus
Q5ZI20
366
39255
Q24
I
V
A
C
E
A
Q
Q
L
P
R
S
H
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
A373
R
E
V
P
G
S
P
A
H
G
V
L
H
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
G307
L
A
V
G
T
M
T
G
D
A
L
L
H
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
I649
H
M
L
I
D
L
G
I
G
G
E
D
G
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
V127
L
A
S
L
I
C
L
V
L
L
P
I
M
F
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
93
74
N.A.
71
71.6
N.A.
31.4
22.4
N.A.
26.5
N.A.
21.2
N.A.
N.A.
21.4
Protein Similarity:
100
98.9
95.1
80.7
N.A.
79.6
80.3
N.A.
48.8
35.2
N.A.
40.7
N.A.
36.1
N.A.
N.A.
33
P-Site Identity:
100
86.6
66.6
46.6
N.A.
26.6
33.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
53.3
60
N.A.
33.3
13.3
N.A.
20
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
9
9
9
0
9
0
9
0
9
9
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
42
0
0
9
0
0
0
9
0
9
9
0
0
9
% D
% Glu:
0
9
0
17
9
0
0
0
0
9
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
9
0
9
9
0
9
17
9
17
0
0
9
0
0
% G
% His:
9
0
0
0
0
17
0
0
25
0
0
0
25
9
9
% H
% Ile:
9
0
0
9
9
9
17
9
0
0
0
9
0
0
0
% I
% Lys:
0
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
9
9
25
42
9
0
25
9
9
17
0
17
25
% L
% Met:
0
9
0
0
0
9
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
42
17
9
0
0
0
% N
% Pro:
0
0
34
9
34
0
9
9
0
9
9
0
0
0
0
% P
% Gln:
42
0
0
0
0
0
9
9
0
0
0
0
0
9
0
% Q
% Arg:
25
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
0
0
25
0
0
9
0
17
25
9
25
50
50
50
0
% S
% Thr:
0
0
0
0
9
0
25
25
0
0
0
0
0
0
0
% T
% Val:
0
9
17
34
0
0
17
9
0
0
9
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _