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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM54A
All Species:
10
Human Site:
S376
Identified Species:
27.5
UniProt:
Q6P444
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P444
NP_001092756.1
385
43384
S376
K
A
V
D
Q
G
I
S
N
T
S
L
L
N
S
Chimpanzee
Pan troglodytes
XP_001170984
386
43488
S377
K
A
V
D
Q
G
I
S
N
T
S
L
L
N
S
Rhesus Macaque
Macaca mulatta
XP_001098719
386
43548
S377
K
A
V
D
Q
G
I
S
N
T
S
L
L
N
S
Dog
Lupus familis
XP_541114
402
45489
S378
T
K
V
Q
C
A
Q
S
L
H
W
Q
G
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VED8
361
40854
F353
S
S
W
E
C
S
P
F
S
S
P
E
T
S
R
Rat
Rattus norvegicus
Q5XII9
289
31712
E281
R
R
K
F
A
L
K
E
E
D
I
S
R
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511702
395
44260
A369
S
I
W
R
A
T
A
A
K
G
S
G
E
K
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085922
312
34166
K304
L
K
S
T
G
K
M
K
T
L
V
E
A
S
H
Zebra Danio
Brachydanio rerio
Q7T3E8
309
34881
K301
L
R
K
K
F
V
L
K
D
D
D
I
S
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
94.3
66.9
N.A.
61
24.4
N.A.
31.6
N.A.
33.2
24.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
97.6
75.1
N.A.
72.4
38.1
N.A.
47.5
N.A.
48.5
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
0
0
N.A.
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
33.3
6.6
N.A.
13.3
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
23
12
12
12
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
0
0
0
0
12
23
12
0
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
12
12
0
0
23
12
0
0
% E
% Phe:
0
0
0
12
12
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
34
0
0
0
12
0
12
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% H
% Ile:
0
12
0
0
0
0
34
0
0
0
12
12
0
0
0
% I
% Lys:
34
23
23
12
0
12
12
23
12
0
0
0
0
34
0
% K
% Leu:
23
0
0
0
0
12
12
0
12
12
0
34
34
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
34
0
0
0
0
34
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
12
% P
% Gln:
0
0
0
12
34
0
12
0
0
0
0
12
0
0
0
% Q
% Arg:
12
23
0
12
0
0
0
0
0
0
0
0
12
0
23
% R
% Ser:
23
12
12
0
0
12
0
45
12
12
45
12
12
23
45
% S
% Thr:
12
0
0
12
0
12
0
0
12
34
0
0
12
0
0
% T
% Val:
0
0
45
0
0
12
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
23
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _