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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNCK All Species: 20.3
Human Site: T175 Identified Species: 34.36
UniProt: Q6P2M8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P2M8 NP_001034671 343 38500 T175 M L G T A C G T P G Y V A P E
Chimpanzee Pan troglodytes XP_516263 370 41302 G180 S V L S T A C G T P G Y V A P
Rhesus Macaque Macaca mulatta XP_001084217 354 39458 T175 M L G T A C G T P G Y A E P A
Dog Lupus familis XP_549361 278 31400 L119 G Y V A P E L L E Q K P Y G K
Cat Felis silvestris
Mouse Mus musculus Q9QYK9 343 38500 T175 M L G T A C G T P G Y V A P E
Rat Rattus norvegicus O70150 343 38420 T175 M L G T A C G T P G Y V A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510983 355 40054 D190 F G L S K I E D G S V M A T A
Chicken Gallus gallus XP_417986 455 50818 T203 I M S T A C G T P G Y V A P E
Frog Xenopus laevis Q6GLS4 377 42906 T184 L I K E P C G T P E Y L A P E
Zebra Danio Brachydanio rerio Q7SY49 436 48676 P184 I K E P C G T P E Y L A P E V
Tiger Blowfish Takifugu rubipres Q9YGM4 421 47309 Y184 D P C G T P E Y L A P E V I G
Fruit Fly Dros. melanogaster Q00168 530 59901 A175 H Q A W F G F A G T P G Y L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49101 513 58063 G228 K M Y R D I V G S A Y Y V A P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42396 490 55361 G185 E A F S E L V G S A Y Y V A P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61 88.6 76.6 N.A. 95.3 95.3 N.A. 75.2 47 40.3 35.5 37 30.1 N.A. N.A. N.A.
Protein Similarity: 100 77 90.6 78.7 N.A. 96.5 96.5 N.A. 85.3 60.2 58.3 53.2 54.6 42.8 N.A. N.A. N.A.
P-Site Identity: 100 0 80 0 N.A. 100 100 N.A. 6.6 80 53.3 0 0 0 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 80 6.6 N.A. 100 100 N.A. 20 93.3 73.3 6.6 0 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 29.4 N.A. 31 N.A. N.A.
Protein Similarity: N.A. 43.6 N.A. 45.3 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 36 8 0 8 0 22 0 15 43 22 15 % A
% Cys: 0 0 8 0 8 43 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 8 0 8 8 8 8 15 0 15 8 0 8 8 8 36 % E
% Phe: 8 0 8 0 8 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 29 8 0 15 43 22 15 36 8 8 0 8 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 8 0 0 0 15 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 8 8 0 8 0 0 0 0 0 8 0 0 0 8 % K
% Leu: 8 29 15 0 0 8 8 8 8 0 8 8 0 8 0 % L
% Met: 29 15 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 15 8 0 8 43 8 15 8 8 43 22 % P
% Gln: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 8 22 0 0 0 0 15 8 0 0 0 0 8 % S
% Thr: 0 0 0 36 15 0 8 43 8 8 0 0 0 8 0 % T
% Val: 0 8 8 0 0 0 15 0 0 0 8 29 29 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 8 0 8 58 22 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _