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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNCK All Species: 12.73
Human Site: S228 Identified Species: 21.54
UniProt: Q6P2M8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P2M8 NP_001034671 343 38500 S228 F S Q I L R A S Y E F D S P F
Chimpanzee Pan troglodytes XP_516263 370 41302 A233 L F E Q I L K A E Y E F D S P
Rhesus Macaque Macaca mulatta XP_001084217 354 39458 D228 P P F Y D E S D P E L F N Q I
Dog Lupus familis XP_549361 278 31400 D172 E F D S P F W D D I S E S A K
Cat Felis silvestris
Mouse Mus musculus Q9QYK9 343 38500 S228 F S Q I L R A S Y E F D S P F
Rat Rattus norvegicus O70150 343 38420 S228 F S Q I L R A S Y E F D S P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510983 355 40054 S243 P F Y D E N D S E L F S Q I L
Chicken Gallus gallus XP_417986 455 50818 Y256 F E K I K E G Y Y E F E S P F
Frog Xenopus laevis Q6GLS4 377 42906 L237 Y E S H D K N L F R K I L H G
Zebra Danio Brachydanio rerio Q7SY49 436 48676 F237 E N H D K N L F R K I L A G D
Tiger Blowfish Takifugu rubipres Q9YGM4 421 47309 K237 R D K N L F L K I L S G D Y E
Fruit Fly Dros. melanogaster Q00168 530 59901 A228 R L Y S Q I K A G A Y D Y P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49101 513 58063 E281 F D A I L H E E I D F E S Q P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42396 490 55361 K238 F R K I L Q G K L E F E I N P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61 88.6 76.6 N.A. 95.3 95.3 N.A. 75.2 47 40.3 35.5 37 30.1 N.A. N.A. N.A.
Protein Similarity: 100 77 90.6 78.7 N.A. 96.5 96.5 N.A. 85.3 60.2 58.3 53.2 54.6 42.8 N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 6.6 N.A. 100 100 N.A. 13.3 53.3 0 0 6.6 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 20 13.3 N.A. 100 100 N.A. 13.3 66.6 20 20 13.3 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 29.4 N.A. 31 N.A. N.A.
Protein Similarity: N.A. 43.6 N.A. 45.3 N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. 46.6 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 22 15 0 8 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 8 15 15 0 8 15 8 8 0 29 15 0 8 % D
% Glu: 15 15 8 0 8 15 8 8 15 43 8 29 0 0 8 % E
% Phe: 43 22 8 0 0 15 0 8 8 0 50 15 0 0 29 % F
% Gly: 0 0 0 0 0 0 15 0 8 0 0 8 0 8 8 % G
% His: 0 0 8 8 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 43 8 8 0 0 15 8 8 8 8 8 8 % I
% Lys: 0 0 22 0 15 8 15 15 0 8 8 0 0 0 8 % K
% Leu: 8 8 0 0 43 8 15 8 8 15 8 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 15 8 0 0 0 0 0 8 8 0 % N
% Pro: 15 8 0 0 8 0 0 0 8 0 0 0 0 36 22 % P
% Gln: 0 0 22 8 8 8 0 0 0 0 0 0 8 15 0 % Q
% Arg: 15 8 0 0 0 22 0 0 8 8 0 0 0 0 0 % R
% Ser: 0 22 8 15 0 0 8 29 0 0 15 8 43 8 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 15 8 0 0 0 8 29 8 8 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _