KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDC4
All Species:
8.79
Human Site:
T939
Identified Species:
19.33
UniProt:
Q6P2E9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2E9
NP_055144.3
1401
151661
T939
A
A
M
G
S
R
L
T
E
H
Q
V
A
E
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089684
1300
138998
E879
Q
E
Y
L
Q
Q
L
E
S
H
M
K
S
R
K
Dog
Lupus familis
XP_546871
1484
160920
M1022
S
A
V
G
S
R
L
M
E
H
Q
G
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UJB9
1406
152465
T944
S
A
V
G
S
R
L
T
E
H
Q
V
A
E
P
Rat
Rattus norvegicus
Q3ZAV8
1407
152577
T945
S
A
V
G
S
R
L
T
E
H
Q
V
V
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414022
1419
155974
V951
A
G
L
A
R
V
Q
V
A
V
G
P
R
D
W
Frog
Xenopus laevis
Q7ZXT3
1391
153901
H930
K
S
P
R
V
S
D
H
L
V
N
L
E
L
Q
Zebra Danio
Brachydanio rerio
Q1LUT1
1384
151831
E925
S
S
Q
S
R
Q
I
E
S
Q
M
S
T
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKK1
1354
149232
A931
K
Q
Q
E
A
A
A
A
L
H
S
K
Q
D
T
Honey Bee
Apis mellifera
XP_396550
1075
119372
L666
T
W
Q
T
T
S
K
L
N
A
L
E
L
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784386
1287
142473
L867
L
E
Q
M
M
S
L
L
Q
T
Q
Q
Q
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
63.8
90.1
N.A.
94.8
94.4
N.A.
N.A.
74.3
62.4
61.6
N.A.
25.1
29.9
N.A.
32.9
Protein Similarity:
100
N.A.
70.2
91.5
N.A.
97
96.8
N.A.
N.A.
84.9
78.5
77.4
N.A.
45.4
48.1
N.A.
50.6
P-Site Identity:
100
N.A.
13.3
66.6
N.A.
86.6
80
N.A.
N.A.
6.6
0
6.6
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
N.A.
26.6
80
N.A.
100
93.3
N.A.
N.A.
20
13.3
33.3
N.A.
20
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
37
0
10
10
10
10
10
10
10
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
19
0
% D
% Glu:
0
19
0
10
0
0
0
19
37
0
0
10
10
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
37
0
0
0
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
55
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% I
% Lys:
19
0
0
0
0
0
10
0
0
0
0
19
0
0
10
% K
% Leu:
10
0
10
10
0
0
55
19
19
0
10
10
10
10
0
% L
% Met:
0
0
10
10
10
0
0
10
0
0
19
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
37
% P
% Gln:
10
10
37
0
10
19
10
0
10
10
46
10
19
0
10
% Q
% Arg:
0
0
0
10
19
37
0
0
0
0
0
0
10
10
0
% R
% Ser:
37
19
0
10
37
28
0
0
19
0
10
10
10
0
0
% S
% Thr:
10
0
0
10
10
0
0
28
0
10
0
0
10
0
10
% T
% Val:
0
0
28
0
10
10
0
10
0
19
0
28
10
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _