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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC73
All Species:
30
Human Site:
S212
Identified Species:
55
UniProt:
Q6P1J9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1J9
NP_078805.3
531
60577
S212
I
T
A
L
K
Q
R
S
F
V
D
A
E
V
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112520
355
40602
N72
T
G
K
N
F
S
K
N
I
F
A
I
L
Q
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_666103
531
60558
S212
I
T
A
L
K
Q
R
S
F
V
D
A
E
V
D
Rat
Rattus norvegicus
Q4V8C8
531
60584
S212
I
T
A
L
K
Q
R
S
F
V
D
A
E
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516577
745
82627
S426
I
T
A
L
K
Q
R
S
F
V
D
A
E
V
D
Chicken
Gallus gallus
Q5ZLM0
531
60679
S212
I
T
A
L
K
Q
R
S
F
V
D
A
E
V
D
Frog
Xenopus laevis
NP_001079512
531
60663
S212
I
T
A
L
K
Q
R
S
F
V
D
A
E
V
D
Zebra Danio
Brachydanio rerio
NP_956642
521
59412
S211
D
I
T
Q
K
Q
R
S
F
V
D
A
E
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649863
538
61366
A212
A
M
G
T
D
L
R
A
I
L
D
Y
D
V
D
Honey Bee
Apis mellifera
XP_395835
525
59540
R207
I
G
M
G
S
D
L
R
V
I
L
M
D
V
D
Nematode Worm
Caenorhab. elegans
NP_500465
535
60290
F209
P
D
F
L
I
K
K
F
Q
F
F
S
E
S
L
Sea Urchin
Strong. purpuratus
XP_001192448
532
61126
S215
V
G
G
L
E
Q
R
S
F
I
D
A
E
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06697
393
44438
N111
L
I
N
W
L
S
G
N
T
E
S
S
Q
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
66.8
N.A.
N.A.
100
99.8
N.A.
67.6
97.7
93.9
88.8
N.A.
58.5
65.1
30.8
62.5
Protein Similarity:
100
N.A.
66.8
N.A.
N.A.
100
99.8
N.A.
70
98.6
96.6
92.6
N.A.
73.4
77.5
52.7
75.3
P-Site Identity:
100
N.A.
0
N.A.
N.A.
100
100
N.A.
100
100
100
73.3
N.A.
26.6
20
13.3
66.6
P-Site Similarity:
100
N.A.
13.3
N.A.
N.A.
100
100
N.A.
100
100
100
73.3
N.A.
46.6
33.3
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
47
0
0
0
0
8
0
0
8
62
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
8
0
0
0
0
70
0
16
0
77
% D
% Glu:
0
0
0
0
8
0
0
0
0
8
0
0
70
0
0
% E
% Phe:
0
0
8
0
8
0
0
8
62
16
8
0
0
0
0
% F
% Gly:
0
24
16
8
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
54
16
0
0
8
0
0
0
16
16
0
8
0
0
0
% I
% Lys:
0
0
8
0
54
8
16
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
62
8
8
8
0
0
8
8
0
8
0
16
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
16
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
62
0
0
8
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
70
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
16
0
62
0
0
8
16
0
8
8
% S
% Thr:
8
47
8
8
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
54
0
0
0
77
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _