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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX57
All Species:
9.7
Human Site:
S462
Identified Species:
19.39
UniProt:
Q6P158
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P158
NP_945314.1
1386
155604
S462
K
T
V
I
P
N
N
S
F
V
S
N
Q
I
P
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
T196
R
Q
R
D
K
D
R
T
R
N
V
L
E
R
S
Rhesus Macaque
Macaca mulatta
XP_001102912
1320
149221
W443
K
I
S
K
R
Y
D
W
Q
A
K
S
V
H
A
Dog
Lupus familis
XP_540155
1382
155439
S457
K
P
V
I
P
N
N
S
F
T
S
S
Q
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D3
1388
155744
T462
K
P
V
V
P
S
N
T
F
L
S
N
Q
M
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521356
483
53990
Chicken
Gallus gallus
Q5ZI74
1231
137685
R383
M
Y
N
M
T
S
L
R
E
L
G
E
N
Q
R
Frog
Xenopus laevis
A3KMI0
1362
153300
R459
Q
L
L
P
P
T
Y
R
N
V
W
L
E
W
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
P441
A
N
I
Y
V
T
Q
P
R
R
I
S
A
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179903
988
110999
A140
P
K
K
E
S
L
Q
A
L
E
D
N
D
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
T320
R
T
K
D
G
Q
V
T
K
T
G
I
S
G
I
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
L516
G
N
L
I
G
D
M
L
V
Y
H
I
Y
E
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.8
93.2
92.5
N.A.
86.8
N.A.
N.A.
32.1
27
31.6
N.A.
N.A.
29.7
N.A.
N.A.
40.3
Protein Similarity:
100
41.2
94.1
95.9
N.A.
92.7
N.A.
N.A.
33.6
45.8
52.1
N.A.
N.A.
46.2
N.A.
N.A.
55
P-Site Identity:
100
0
6.6
73.3
N.A.
53.3
N.A.
N.A.
0
0
13.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
20
80
N.A.
86.6
N.A.
N.A.
0
20
33.3
N.A.
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
0
9
0
0
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
17
9
0
0
0
9
0
9
0
9
% D
% Glu:
0
0
0
9
0
0
0
0
9
9
0
9
17
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
17
0
0
0
0
0
17
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
9
9
25
0
0
0
0
0
0
9
17
0
25
9
% I
% Lys:
34
9
17
9
9
0
0
0
9
0
9
0
0
0
0
% K
% Leu:
0
9
17
0
0
9
9
9
9
17
0
17
0
0
9
% L
% Met:
9
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
17
9
0
0
17
25
0
9
9
0
25
9
0
0
% N
% Pro:
9
17
0
9
34
0
0
9
0
0
0
0
0
0
9
% P
% Gln:
9
9
0
0
0
9
17
0
9
0
0
0
25
9
0
% Q
% Arg:
17
0
9
0
9
0
9
17
17
9
0
0
0
9
9
% R
% Ser:
0
0
9
0
9
17
0
17
0
0
25
25
9
0
25
% S
% Thr:
0
17
0
0
9
17
0
25
0
17
0
0
0
0
0
% T
% Val:
0
0
25
9
9
0
9
0
9
17
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
9
0
0
9
9
% W
% Tyr:
0
9
0
9
0
9
9
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _