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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40B
All Species:
25.45
Human Site:
S86
Identified Species:
50.91
UniProt:
Q6NWY9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NWY9
NP_001026868.1
871
99358
S86
P
G
A
D
T
A
S
S
A
V
A
G
T
G
P
Chimpanzee
Pan troglodytes
XP_001144883
893
101489
S108
P
G
A
D
T
A
S
S
A
L
A
G
T
G
P
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
S121
P
G
A
D
T
A
S
S
A
V
A
G
T
G
P
Dog
Lupus familis
XP_534809
997
112581
S210
P
G
A
D
T
A
S
S
A
V
A
G
T
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80W14
870
99281
S86
P
G
A
D
T
A
S
S
A
V
A
G
T
G
P
Rat
Rattus norvegicus
NP_001128055
867
99008
S86
P
G
A
D
T
A
S
S
A
V
P
G
T
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
G115
R
V
Y
T
T
S
V
G
G
F
S
Q
N
S
V
Chicken
Gallus gallus
NP_989492
853
96992
S121
Q
T
A
T
T
N
S
S
G
S
E
E
H
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
S100
T
S
T
T
S
T
E
S
S
P
D
E
Q
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
S53
A
F
G
V
M
A
T
S
T
E
W
T
E
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
R59
P
H
V
A
A
P
T
R
P
S
P
M
L
V
P
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
Q170
L
A
Q
K
E
T
V
Q
G
S
G
D
E
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.6
85
N.A.
95.5
95
N.A.
57
57.6
N.A.
60.8
N.A.
40.4
N.A.
31.9
34.6
Protein Similarity:
100
97.5
94
86
N.A.
97.5
97.1
N.A.
71.8
71.6
N.A.
74.7
N.A.
57.6
N.A.
52
44.3
P-Site Identity:
100
93.3
100
100
N.A.
100
93.3
N.A.
6.6
26.6
N.A.
6.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
26.6
N.A.
20
N.A.
20
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
59
9
9
59
0
0
50
0
42
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
0
0
9
9
17
17
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
50
9
0
0
0
0
9
25
0
9
50
0
50
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
34
% K
% Leu:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
59
0
0
0
0
9
0
0
9
9
17
0
0
9
59
% P
% Gln:
9
0
9
0
0
0
0
9
0
0
0
9
9
0
0
% Q
% Arg:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
9
9
59
75
9
25
9
0
0
17
0
% S
% Thr:
9
9
9
25
67
17
17
0
9
0
0
9
50
0
0
% T
% Val:
0
9
9
9
0
0
17
0
0
42
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _