KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM214
All Species:
16.36
Human Site:
S590
Identified Species:
36
UniProt:
Q6NUQ4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUQ4
NP_060197.4
689
77151
S590
H
L
A
W
F
G
D
S
L
T
S
L
S
Q
R
Chimpanzee
Pan troglodytes
XP_001153665
689
77137
S590
H
L
A
W
F
G
D
S
L
T
S
L
S
Q
R
Rhesus Macaque
Macaca mulatta
XP_001088228
597
66501
S523
T
S
G
F
L
P
A
S
Q
Q
A
C
A
K
L
Dog
Lupus familis
XP_853692
656
73702
S559
H
L
A
W
F
G
D
S
L
A
S
L
S
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM55
687
76411
S590
Y
L
A
C
F
S
D
S
L
A
G
F
F
Q
R
Rat
Rattus norvegicus
A1L1L2
685
76548
S588
Y
L
A
F
F
S
D
S
L
A
G
V
L
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426216
680
75753
R581
Y
L
S
W
A
G
E
R
L
P
W
L
L
E
W
Frog
Xenopus laevis
A1L2I9
679
76789
N580
L
L
S
Y
A
K
D
N
L
P
R
L
I
E
W
Zebra Danio
Brachydanio rerio
XP_700034
672
76079
N575
L
M
L
W
M
Q
E
N
L
P
L
L
L
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788023
677
75663
F600
K
W
P
V
V
A
K
F
I
D
Q
Y
V
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190838
459
53200
I386
A
P
I
W
L
D
W
I
L
A
Q
T
V
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
84.9
84.6
N.A.
81.4
82.2
N.A.
N.A.
57.7
53.7
53.5
N.A.
22.5
N.A.
N.A.
25.6
Protein Similarity:
100
98.9
85.4
88.5
N.A.
87.8
89.2
N.A.
N.A.
73
71.1
70.5
N.A.
41.6
N.A.
N.A.
38.9
P-Site Identity:
100
100
6.6
93.3
N.A.
53.3
53.3
N.A.
N.A.
33.3
26.6
20
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
60
73.3
N.A.
N.A.
60
53.3
40
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
46
0
19
10
10
0
0
37
10
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
10
55
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
19
0
0
0
0
0
0
28
0
% E
% Phe:
0
0
0
19
46
0
0
10
0
0
0
10
10
0
0
% F
% Gly:
0
0
10
0
0
37
0
0
0
0
19
0
0
0
0
% G
% His:
28
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
0
0
0
10
10
0
0
0
10
0
10
% I
% Lys:
10
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% K
% Leu:
19
64
10
0
19
0
0
0
82
0
10
55
28
0
10
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
10
% N
% Pro:
0
10
10
0
0
10
0
0
0
28
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
10
19
0
0
46
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
46
% R
% Ser:
0
10
19
0
0
19
0
55
0
0
28
0
28
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
19
0
10
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
10
19
0
0
% V
% Trp:
0
10
0
55
0
0
10
0
0
0
10
0
0
0
28
% W
% Tyr:
28
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _