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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4F22
All Species:
9.09
Human Site:
S499
Identified Species:
25
UniProt:
Q6NT55
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NT55
NP_775754.2
531
61958
S499
T
L
L
R
F
R
L
S
V
D
R
T
R
K
V
Chimpanzee
Pan troglodytes
XP_512456
531
61967
S499
T
L
L
R
F
R
L
S
V
D
R
T
R
K
V
Rhesus Macaque
Macaca mulatta
XP_001111971
531
62052
R499
T
L
L
R
F
R
L
R
V
D
R
T
R
K
V
Dog
Lupus familis
XP_541984
531
61918
S499
T
L
L
R
F
R
L
S
V
D
R
T
R
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP75
524
59782
L492
T
L
L
R
F
R
L
L
P
D
D
K
E
P
R
Rat
Rattus norvegicus
P51870
526
60663
L494
T
L
L
R
F
R
V
L
P
D
D
K
E
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506150
522
60854
V490
T
L
L
R
F
K
L
V
V
D
R
T
K
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001165650
528
61314
R498
I
L
Y
K
F
H
V
R
L
D
E
T
K
A
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA27
535
60739
E505
V
L
R
K
Y
K
I
E
A
V
D
R
R
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.8
91.5
N.A.
61.3
62.1
N.A.
77.4
N.A.
64
N.A.
N.A.
33.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.4
95.8
N.A.
79
77.7
N.A.
88.3
N.A.
80.7
N.A.
N.A.
54.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
53.3
46.6
N.A.
80
N.A.
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
53.3
53.3
N.A.
93.3
N.A.
60
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
89
34
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
12
0
23
12
0
% E
% Phe:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
23
0
23
0
0
0
0
0
23
23
56
0
% K
% Leu:
0
100
78
0
0
0
67
23
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
23
0
0
0
0
23
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
78
0
67
0
23
0
0
56
12
56
0
23
% R
% Ser:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
78
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% T
% Val:
12
0
0
0
0
0
23
12
56
12
0
0
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _