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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A25
All Species:
35.76
Human Site:
S273
Identified Species:
60.51
UniProt:
Q6KCM7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6KCM7
NP_001006642.1
469
52663
S273
Q
I
K
R
L
V
G
S
D
Q
E
T
L
R
I
Chimpanzee
Pan troglodytes
XP_001153366
469
52663
S273
Q
I
K
R
L
V
G
S
D
Q
E
T
L
R
I
Rhesus Macaque
Macaca mulatta
XP_001088378
468
52373
G272
Q
I
K
R
A
I
L
G
Q
Q
E
T
L
H
V
Dog
Lupus familis
XP_862510
469
52735
S273
Q
I
K
R
L
V
G
S
D
Q
E
T
L
R
I
Cat
Felis silvestris
Mouse
Mus musculus
A2ASZ8
469
52602
S273
Q
M
K
R
L
V
G
S
D
Q
E
T
L
R
I
Rat
Rattus norvegicus
Q8K3P6
469
52677
S273
Q
M
K
R
L
V
G
S
D
Q
E
T
L
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505563
469
52720
T273
Q
I
K
R
L
V
G
T
D
Q
E
T
L
R
I
Chicken
Gallus gallus
XP_415513
469
52817
T273
Q
I
K
R
F
I
G
T
D
Q
E
M
L
R
I
Frog
Xenopus laevis
Q7ZYD5
514
56789
S318
Q
I
K
R
I
I
G
S
N
Q
E
T
L
G
I
Zebra Danio
Brachydanio rerio
A2CEQ0
469
52693
S273
Q
I
K
R
L
I
G
S
N
Q
E
T
L
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
K337
K
R
L
I
Q
K
K
K
G
N
E
E
I
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P29518
436
46609
T244
A
L
A
G
F
A
S
T
L
C
T
Y
P
M
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65023
381
41798
R190
D
Q
L
S
V
I
G
R
L
A
A
G
A
C
A
Baker's Yeast
Sacchar. cerevisiae
P48233
545
61252
R340
M
T
K
L
E
G
C
R
D
T
K
D
L
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
63.7
97.8
N.A.
97.4
97
N.A.
96.3
93.5
76.2
85.7
N.A.
N.A.
N.A.
39.7
N.A.
Protein Similarity:
100
99.7
75.6
99.1
N.A.
98.7
98.7
N.A.
98.7
98
82.8
94
N.A.
N.A.
N.A.
58.1
N.A.
P-Site Identity:
100
100
53.3
100
N.A.
93.3
93.3
N.A.
93.3
73.3
73.3
80
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
100
86.6
93.3
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
28.3
N.A.
25.8
28.8
N.A.
Protein Similarity:
N.A.
45.4
N.A.
42.8
47.5
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
0
0
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
0
58
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
79
8
0
0
8
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
72
8
8
0
0
8
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
58
0
8
8
36
0
0
0
0
0
0
8
0
65
% I
% Lys:
8
0
79
0
0
8
8
8
0
0
8
0
0
0
8
% K
% Leu:
0
8
15
8
50
0
8
0
15
0
0
0
79
0
0
% L
% Met:
8
15
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
72
8
0
0
8
0
0
0
8
72
0
0
0
0
0
% Q
% Arg:
0
8
0
72
0
0
0
15
0
0
0
0
0
50
0
% R
% Ser:
0
0
0
8
0
0
8
50
0
0
0
0
0
15
0
% S
% Thr:
0
8
0
0
0
0
0
22
0
8
8
65
0
0
8
% T
% Val:
0
0
0
0
8
43
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _