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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO7
All Species:
16.67
Human Site:
T248
Identified Species:
40.74
UniProt:
Q6IWH7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IWH7
NP_001001666.1
933
105531
T248
L
G
S
D
N
Q
D
T
F
F
T
S
T
K
R
Chimpanzee
Pan troglodytes
XP_001161327
918
103229
T248
L
G
S
D
N
Q
D
T
F
F
T
S
T
K
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543329
1212
132018
T404
L
G
S
D
N
P
D
T
F
F
S
S
T
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q14AT5
859
97109
S230
L
L
A
E
G
V
F
S
A
A
F
P
L
H
D
Rat
Rattus norvegicus
Q6IFT6
860
97152
S230
L
L
A
E
G
V
F
S
A
A
F
P
L
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509105
975
114441
T288
F
T
I
N
N
K
D
T
F
F
S
N
S
T
R
Chicken
Gallus gallus
NP_001161856
903
106453
K222
Y
G
T
E
E
G
K
K
K
F
G
I
K
R
L
Frog
Xenopus laevis
NP_001128709
979
113207
S235
F
D
M
S
D
K
E
S
F
F
D
S
K
T
R
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
V52
N
G
G
A
E
L
L
V
D
Q
L
L
F
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
F220
I
M
E
S
Q
D
T
F
F
P
N
N
I
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
N.A.
57
N.A.
77.2
76.8
N.A.
36.8
36.9
35
23.4
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
95.5
N.A.
64.5
N.A.
81.6
81.9
N.A.
55.9
56.8
54.8
40.1
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
N.A.
80
N.A.
6.6
6.6
N.A.
40
13.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
86.6
N.A.
26.6
26.6
N.A.
73.3
33.3
53.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
10
0
0
0
0
20
20
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
30
10
10
40
0
10
0
10
0
0
10
20
% D
% Glu:
0
0
10
30
20
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
20
0
0
0
0
0
20
10
60
60
20
0
10
0
0
% F
% Gly:
0
50
10
0
20
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
20
10
10
10
0
0
0
20
20
0
% K
% Leu:
50
20
0
0
0
10
10
0
0
0
10
10
20
0
10
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
40
0
0
0
0
0
10
20
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
10
0
20
0
10
0
% P
% Gln:
0
0
0
0
10
20
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
50
% R
% Ser:
0
0
30
20
0
0
0
30
0
0
20
40
10
0
0
% S
% Thr:
0
10
10
0
0
0
10
40
0
0
20
0
30
20
0
% T
% Val:
0
0
0
0
0
20
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _