KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF425
All Species:
16.97
Human Site:
S325
Identified Species:
74.67
UniProt:
Q6IV72
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IV72
NP_001001661.1
752
87721
S325
T
E
H
L
R
L
H
S
G
E
K
P
F
Q
C
Chimpanzee
Pan troglodytes
XP_519465
656
76398
S260
T
E
H
L
R
L
H
S
G
E
K
P
F
Q
C
Rhesus Macaque
Macaca mulatta
XP_001098558
660
76843
K263
H
L
S
Q
H
S
G
K
R
P
F
H
C
P
E
Dog
Lupus familis
XP_539898
1095
126546
T397
T
K
H
L
R
V
H
T
G
E
K
P
F
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
P10076
861
97970
T325
T
E
H
M
R
S
H
T
G
E
K
P
Y
Q
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P18751
898
101149
T365
T
V
H
R
R
I
H
T
G
E
R
P
F
S
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.8
48.4
N.A.
33.9
N.A.
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87
85.6
56.3
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
84
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
0
0
0
0
0
0
0
84
0
0
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
67
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
84
0
0
0
0
0
0
% G
% His:
17
0
84
0
17
0
84
0
0
0
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
0
0
17
0
0
67
0
0
0
0
% K
% Leu:
0
17
0
50
0
34
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
17
0
84
0
17
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
0
67
0
% Q
% Arg:
0
0
0
17
84
0
0
0
17
0
17
0
0
0
0
% R
% Ser:
0
0
17
0
0
34
0
34
0
0
0
0
0
17
0
% S
% Thr:
84
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
0
17
0
0
0
17
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _