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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5RL All Species: 9.09
Human Site: S25 Identified Species: 25
UniProt: Q6IPT4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IPT4 NP_001026842.2 314 35761 S25 R P T E P L P S Q C C G S G C
Chimpanzee Pan troglodytes XP_513422 314 35744 S25 R P T E P L P S Q C C G S G C
Rhesus Macaque Macaca mulatta XP_001113894 182 20934
Dog Lupus familis XP_853222 314 35796 S25 R P V E P L P S Q C C G S G C
Cat Felis silvestris
Mouse Mus musculus B1AS42 316 35865 C27 E P L P S Q C C G S G C S P C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396639 313 35090 I23 V L A A V G T I A V I G L A V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002315404 280 31090
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P83291 328 35969 S27 A F G S Q S K S G S G A F R F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RXL1 310 33982 F24 I P A G L L V F G T V I V K K
Conservation
Percent
Protein Identity: 100 99.3 55 84.7 N.A. 78.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 27 N.A. N.A.
Protein Similarity: 100 99.6 56 91.7 N.A. 88.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 48 N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 0 93.3 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: 31.5 N.A. N.A. 23.7 N.A. 28.9
Protein Similarity: 45.8 N.A. N.A. 41.7 N.A. 43.6
P-Site Identity: 0 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 0 N.A. N.A. 6.6 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 23 12 0 0 0 0 12 0 0 12 0 12 0 % A
% Cys: 0 0 0 0 0 0 12 12 0 34 34 12 0 0 45 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 12 0 0 0 0 0 12 0 0 0 0 12 0 12 % F
% Gly: 0 0 12 12 0 12 0 0 34 0 23 45 0 34 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 12 0 0 12 12 0 0 0 % I
% Lys: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 12 % K
% Leu: 0 12 12 0 12 45 0 0 0 0 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 56 0 12 34 0 34 0 0 0 0 0 0 12 0 % P
% Gln: 0 0 0 0 12 12 0 0 34 0 0 0 0 0 0 % Q
% Arg: 34 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 0 0 12 12 12 0 45 0 23 0 0 45 0 0 % S
% Thr: 0 0 23 0 0 0 12 0 0 12 0 0 0 0 0 % T
% Val: 12 0 12 0 12 0 12 0 0 12 12 0 12 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _