KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7B
All Species:
30.91
Human Site:
S268
Identified Species:
52.31
UniProt:
Q6IAN0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IAN0
NP_056325.2
325
35119
S268
T
T
T
A
Q
G
R
S
P
V
E
V
A
Q
D
Chimpanzee
Pan troglodytes
XP_511344
325
35116
S268
T
T
T
A
Q
G
R
S
P
V
E
V
A
Q
D
Rhesus Macaque
Macaca mulatta
XP_001103593
371
40181
S314
T
T
T
A
Q
G
R
S
P
V
E
V
A
H
D
Dog
Lupus familis
XP_536670
325
35359
S268
K
T
T
A
Q
G
R
S
P
V
E
V
A
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99J47
323
34968
S266
K
N
T
A
Q
G
R
S
A
A
E
V
A
Q
D
Rat
Rattus norvegicus
Q5RJY4
325
35324
S268
K
N
T
A
Q
G
R
S
A
V
E
V
A
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511308
544
58832
N487
K
T
T
S
E
G
R
N
A
A
E
V
A
Q
E
Chicken
Gallus gallus
Q6PUF4
287
31460
L243
S
P
A
A
E
A
A
L
A
I
I
R
G
G
A
Frog
Xenopus laevis
Q0IH28
323
35135
T252
K
N
T
A
D
G
R
T
P
E
E
V
A
Q
T
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
D253
R
T
T
A
T
G
A
D
P
V
D
V
A
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
S267
E
T
T
A
K
G
M
S
P
D
K
L
A
E
R
Honey Bee
Apis mellifera
XP_394428
317
36148
Y262
K
T
I
Q
E
G
Y
Y
P
E
Y
V
A
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793326
411
43892
S355
S
T
T
A
G
G
M
S
T
V
Y
V
A
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
D223
Q
A
K
N
V
Y
K
D
T
T
P
L
M
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
84.9
87
N.A.
77.5
77.5
N.A.
46.3
24.9
63.6
54.7
N.A.
43.2
45.2
N.A.
37.7
Protein Similarity:
100
99.3
86.7
93.2
N.A.
88.3
88
N.A.
54
46.1
78.1
74.4
N.A.
61.6
63.3
N.A.
53.7
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
80
N.A.
53.3
6.6
60
60
N.A.
46.6
33.3
N.A.
53.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
80
N.A.
80
26.6
66.6
73.3
N.A.
73.3
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
79
0
8
15
0
29
15
0
0
86
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
15
0
8
8
0
0
15
58
% D
% Glu:
8
0
0
0
22
0
0
0
0
15
58
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
86
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
43
0
8
0
8
0
8
0
0
0
8
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
8
0
0
% M
% Asn:
0
22
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
58
0
8
0
0
0
0
% P
% Gln:
8
0
0
8
43
0
0
0
0
0
0
0
0
43
0
% Q
% Arg:
8
0
0
0
0
0
58
0
0
0
0
8
0
8
15
% R
% Ser:
15
0
0
8
0
0
0
58
0
0
0
0
0
0
0
% S
% Thr:
22
65
79
0
8
0
0
8
15
8
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
50
0
79
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
8
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _