KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM2
All Species:
0
Human Site:
T378
Identified Species:
0
UniProt:
Q6H9L7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6H9L7
NP_872315.2
571
63906
T378
P
G
T
E
D
K
D
T
L
G
L
P
S
E
E
Chimpanzee
Pan troglodytes
XP_525268
582
65976
A389
I
E
D
T
F
R
T
A
A
T
E
V
S
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542888
464
52096
A272
E
D
T
F
R
T
A
A
T
E
V
S
L
L
A
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
A262
E
D
T
F
R
T
A
A
T
E
V
S
L
L
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
A240
I
E
D
T
F
R
T
A
A
T
E
V
S
L
L
Chicken
Gallus gallus
XP_426452
491
55855
I299
C
P
G
A
E
G
E
I
V
F
P
T
E
E
T
Frog
Xenopus laevis
Q8QFV1
449
50956
A257
E
D
T
F
R
T
A
A
T
E
V
S
L
L
A
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
A269
E
D
A
F
K
T
A
A
T
E
V
S
L
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
Q262
D
L
L
V
K
L
F
Q
S
L
R
N
A
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
R206
S
D
L
P
S
A
T
R
S
N
Q
G
F
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
N.A.
39.7
N.A.
38.3
N.A.
N.A.
37.1
46.9
37.4
38.1
N.A.
N.A.
24.3
N.A.
25.3
Protein Similarity:
100
46.7
N.A.
51.8
N.A.
51.1
N.A.
N.A.
48.1
59.8
50.9
51.3
N.A.
N.A.
40.4
N.A.
41.1
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
6.6
N.A.
N.A.
6.6
6.6
6.6
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
13.3
N.A.
13.3
N.A.
13.3
N.A.
N.A.
13.3
26.6
13.3
6.6
N.A.
N.A.
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
40
60
20
0
0
0
10
0
40
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
50
20
0
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
40
20
0
10
10
0
10
0
0
40
20
0
10
20
10
% E
% Phe:
0
0
0
40
20
0
10
0
0
10
0
0
10
0
0
% F
% Gly:
0
10
10
0
0
10
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
20
0
0
10
0
0
10
10
10
0
40
60
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
10
10
0
10
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
30
20
0
10
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
0
0
20
0
0
40
30
0
0
% S
% Thr:
0
0
40
20
0
40
30
10
40
20
0
10
0
10
20
% T
% Val:
0
0
0
10
0
0
0
0
10
0
40
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _