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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM2
All Species:
2.12
Human Site:
T163
Identified Species:
5.19
UniProt:
Q6H9L7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6H9L7
NP_872315.2
571
63906
T163
L
H
Q
H
G
C
W
T
V
T
E
P
A
A
L
Chimpanzee
Pan troglodytes
XP_525268
582
65976
S180
T
T
S
E
T
S
F
S
L
S
K
E
A
P
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542888
464
52096
H78
H
L
D
H
Q
A
A
H
Q
P
F
P
R
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
H68
P
E
E
H
Q
V
V
H
Q
P
F
P
R
Q
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
A46
E
Y
P
D
H
R
A
A
H
R
P
F
P
R
Q
Chicken
Gallus gallus
XP_426452
491
55855
L105
E
E
S
L
P
F
V
L
D
L
Q
S
L
P
G
Frog
Xenopus laevis
Q8QFV1
449
50956
T63
Q
E
Y
L
D
E
A
T
R
R
A
F
P
K
H
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
Q75
V
A
H
I
P
A
S
Q
P
W
A
Q
S
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
L68
R
K
K
R
N
E
R
L
V
E
E
L
V
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
L12
I
T
S
V
W
P
Y
L
L
P
L
A
I
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
N.A.
39.7
N.A.
38.3
N.A.
N.A.
37.1
46.9
37.4
38.1
N.A.
N.A.
24.3
N.A.
25.3
Protein Similarity:
100
46.7
N.A.
51.8
N.A.
51.1
N.A.
N.A.
48.1
59.8
50.9
51.3
N.A.
N.A.
40.4
N.A.
41.1
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
13.3
N.A.
N.A.
0
0
6.6
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
40
N.A.
13.3
N.A.
20
N.A.
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
20
30
10
0
0
20
10
20
10
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
20
30
10
10
0
20
0
0
0
10
20
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
20
20
0
10
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
20
% G
% His:
10
10
10
30
10
0
0
20
10
0
0
0
0
0
10
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
0
10
0
0
10
0
% K
% Leu:
10
10
0
20
0
0
0
30
20
10
10
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
20
10
0
0
10
30
10
30
20
40
0
% P
% Gln:
10
0
10
0
20
0
0
10
20
0
10
10
0
20
10
% Q
% Arg:
10
0
0
10
0
10
10
0
10
20
0
0
20
10
30
% R
% Ser:
0
0
30
0
0
10
10
10
0
10
0
10
10
0
0
% S
% Thr:
10
20
0
0
10
0
0
20
0
10
0
0
0
0
10
% T
% Val:
10
0
0
10
0
10
20
0
20
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _