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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM2
All Species:
13.33
Human Site:
S277
Identified Species:
32.59
UniProt:
Q6H9L7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6H9L7
NP_872315.2
571
63906
S277
E
E
D
E
D
Y
P
S
E
D
I
E
G
E
D
Chimpanzee
Pan troglodytes
XP_525268
582
65976
Y298
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542888
464
52096
S184
D
Y
K
Y
D
S
T
S
D
D
S
N
F
L
N
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
S174
D
D
K
Y
D
S
T
S
D
D
S
N
F
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
T152
Q
D
Y
K
Y
D
S
T
T
E
D
S
N
F
L
Chicken
Gallus gallus
XP_426452
491
55855
T211
E
E
E
E
E
D
Y
T
A
E
Y
E
E
E
E
Frog
Xenopus laevis
Q8QFV1
449
50956
T169
D
Y
K
Y
D
S
T
T
E
D
S
N
F
L
N
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
T181
D
Y
P
Y
E
S
N
T
E
D
S
N
F
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
V174
K
S
K
K
E
S
F
V
V
I
E
R
N
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
I118
E
E
E
D
A
A
E
I
D
N
R
L
P
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
N.A.
39.7
N.A.
38.3
N.A.
N.A.
37.1
46.9
37.4
38.1
N.A.
N.A.
24.3
N.A.
25.3
Protein Similarity:
100
46.7
N.A.
51.8
N.A.
51.1
N.A.
N.A.
48.1
59.8
50.9
51.3
N.A.
N.A.
40.4
N.A.
41.1
P-Site Identity:
100
20
N.A.
20
N.A.
20
N.A.
N.A.
0
33.3
20
13.3
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
40
N.A.
40
N.A.
40
N.A.
N.A.
33.3
66.6
40
33.3
N.A.
N.A.
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
20
20
10
50
20
0
0
40
50
10
0
10
10
20
% D
% Glu:
30
30
20
20
30
0
10
0
30
20
10
20
10
20
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
40
10
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% I
% Lys:
10
0
40
20
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
40
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
40
20
0
20
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
10
10
0
0
0
50
10
30
0
10
40
20
0
10
30
% S
% Thr:
0
0
0
0
0
0
30
40
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
10
40
10
20
10
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _