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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR139
All Species:
18.18
Human Site:
S222
Identified Species:
50
UniProt:
Q6DWJ6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DWJ6
NP_001002911.1
353
40679
S222
N
F
R
L
R
G
Y
S
T
G
K
T
T
A
I
Chimpanzee
Pan troglodytes
XP_523704
374
41110
I236
H
C
L
T
V
Y
F
I
P
C
G
V
F
L
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547108
473
53300
S342
N
F
R
L
R
G
Y
S
T
G
K
T
T
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80UC8
345
39740
S214
N
F
R
L
R
G
Y
S
T
G
K
T
T
A
I
Rat
Rattus norvegicus
P0C0W8
345
39724
S214
N
F
R
L
R
G
Y
S
T
G
K
T
T
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508798
345
39948
S214
N
F
R
L
R
G
Y
S
T
G
K
T
T
A
I
Chicken
Gallus gallus
O93603
395
44679
F221
G
L
I
A
R
I
L
F
L
N
P
I
P
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338923
364
40867
K233
L
R
G
Y
S
T
G
K
T
T
A
I
L
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11082
434
50008
I224
L
T
V
L
N
I
Q
I
M
I
A
F
R
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.5
N.A.
72.7
N.A.
94
94
N.A.
86.4
23.5
N.A.
70.5
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
100
57.2
N.A.
73.1
N.A.
96
96
N.A.
88.6
44
N.A.
80.2
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
6.6
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
100
13.3
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
23
0
0
56
12
% A
% Cys:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
56
0
0
0
0
12
12
0
0
0
12
12
0
0
% F
% Gly:
12
0
12
0
0
56
12
0
0
56
12
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
23
0
23
0
12
0
23
0
0
56
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
56
0
0
12
0
% K
% Leu:
23
12
12
67
0
0
12
0
12
0
0
0
12
23
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
56
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
12
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
56
0
67
0
0
0
0
0
0
0
12
0
12
% R
% Ser:
0
0
0
0
12
0
0
56
0
0
0
0
0
12
0
% S
% Thr:
0
12
0
12
0
12
0
0
67
12
0
56
56
0
0
% T
% Val:
0
0
12
0
12
0
0
0
0
0
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
12
56
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _