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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQSEC1 All Species: 15.45
Human Site: S361 Identified Species: 42.5
UniProt: Q6DN90 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DN90 NP_001127854.1 963 108314 S361 D T D T S C R S T P S L E R Q
Chimpanzee Pan troglodytes XP_516294 1034 115556 S432 D T D T S C R S T P S L E R Q
Rhesus Macaque Macaca mulatta XP_001083503 963 108344 S361 D T D T S C R S T P S L E R Q
Dog Lupus familis XP_541746 3034 332646 S2421 D T D T S C R S T P S L E R Q
Cat Felis silvestris
Mouse Mus musculus Q8R0S2 961 107997 P361 D T S C R S T P S L E R P E P
Rat Rattus norvegicus Q76M68 1194 129000 A412 L A K S I D D A L S T W S L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414318 1243 140561 T449 H K D D K I D T D T S C R S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922323 1378 154711 T602 D E K A D T D T S C R S T P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396854 1053 118476 M380 S Q E S G S S M H Y Y N P Q E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.8 99.5 29.6 N.A. 95.6 33.6 N.A. N.A. 67.9 N.A. 59.7 N.A. N.A. 31.5 N.A. N.A.
Protein Similarity: 100 92.2 99.6 30.2 N.A. 97.4 47.7 N.A. N.A. 72.4 N.A. 64.3 N.A. N.A. 48 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 0 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 26.6 N.A. N.A. 20 N.A. 20 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 12 0 45 0 0 0 12 0 12 0 0 0 % C
% Asp: 67 0 56 12 12 12 34 0 12 0 0 0 0 0 0 % D
% Glu: 0 12 12 0 0 0 0 0 0 0 12 0 45 12 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % G
% His: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 23 0 12 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 12 0 0 0 0 0 0 0 12 12 0 45 0 12 0 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 12 0 45 0 0 23 12 12 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 0 0 0 12 45 % Q
% Arg: 0 0 0 0 12 0 45 0 0 0 12 12 12 45 0 % R
% Ser: 12 0 12 23 45 23 12 45 23 12 56 12 12 12 12 % S
% Thr: 0 56 0 45 0 12 12 23 45 12 12 0 12 0 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 12 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _