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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5R2
All Species:
42.73
Human Site:
Y223
Identified Species:
78.33
UniProt:
Q6BCY4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6BCY4
NP_057313.2
276
31458
Y223
R
P
P
I
G
W
K
Y
S
S
G
F
V
T
A
Chimpanzee
Pan troglodytes
XP_001166922
336
37776
Y283
R
P
P
I
G
W
K
Y
S
S
G
F
V
T
A
Rhesus Macaque
Macaca mulatta
XP_001099164
468
51616
Y415
R
P
P
I
G
W
K
Y
S
S
G
F
V
T
A
Dog
Lupus familis
XP_542485
636
70694
Y583
R
P
P
V
G
W
K
Y
S
S
G
Y
I
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3KNK3
276
31342
Y223
R
P
P
S
D
W
K
Y
S
S
G
F
V
S
A
Rat
Rattus norvegicus
Q6AY12
276
31220
Y223
R
P
P
S
G
W
E
Y
S
S
G
F
I
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518224
300
33346
Y247
Q
P
P
K
G
W
S
Y
G
R
G
F
V
T
A
Chicken
Gallus gallus
Q5ZHX7
304
33589
Y251
R
P
P
Q
D
W
K
Y
S
S
G
F
V
T
A
Frog
Xenopus laevis
Q5PQA4
296
32646
Y243
R
P
P
Q
G
W
K
Y
G
S
G
F
V
T
A
Zebra Danio
Brachydanio rerio
Q0P487
309
34369
Y256
R
P
S
E
G
W
K
Y
S
E
G
F
V
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623086
308
34610
Y255
T
S
S
E
N
W
Q
Y
S
T
G
H
I
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194747
350
39037
Y297
R
P
G
E
G
W
Q
Y
S
S
G
F
V
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P17571
621
69754
S568
P
E
E
G
W
K
Y
S
V
G
F
V
T
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
56.6
37.5
N.A.
82.2
82.6
N.A.
55.3
62.8
60.8
56.3
N.A.
N.A.
52.2
N.A.
47.4
Protein Similarity:
100
80.6
57.4
40.8
N.A.
91.3
93.1
N.A.
71
75.6
77.6
68.9
N.A.
N.A.
70.1
N.A.
62.5
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
66.6
86.6
86.6
73.3
N.A.
N.A.
33.3
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
73.3
86.6
86.6
73.3
N.A.
N.A.
53.3
N.A.
80
Percent
Protein Identity:
N.A.
21.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
24
0
0
8
0
0
8
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
77
0
0
0
% F
% Gly:
0
0
8
8
70
0
0
0
16
8
93
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
24
0
0
0
0
0
0
0
0
24
0
0
% I
% Lys:
0
0
0
8
0
8
62
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
16
0
% N
% Pro:
8
85
70
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
16
0
0
16
0
0
0
0
0
0
0
0
% Q
% Arg:
77
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
8
16
16
0
0
8
8
77
70
0
0
0
16
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
8
62
0
% T
% Val:
0
0
0
8
0
0
0
0
8
0
0
8
70
0
0
% V
% Trp:
0
0
0
0
8
93
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
93
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _