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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R2 All Species: 40.61
Human Site: Y18 Identified Species: 74.44
UniProt: Q6BCY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6BCY4 NP_057313.2 276 31458 Y18 L Q D P E A K Y P L P L I E K
Chimpanzee Pan troglodytes XP_001166922 336 37776 Y78 L Q D P E A K Y P L P L I E K
Rhesus Macaque Macaca mulatta XP_001099164 468 51616 Y210 L Q D P E A K Y P L P L I E K
Dog Lupus familis XP_542485 636 70694 Y378 L Q D S E A K Y L L P L I E K
Cat Felis silvestris
Mouse Mus musculus Q3KNK3 276 31342 Y18 L Q D P E A K Y P L P L I E K
Rat Rattus norvegicus Q6AY12 276 31220 Y18 L Q D P E A K Y P L P L I E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518224 300 33346 Y42 L L D P N E K Y L L R L L D R
Chicken Gallus gallus Q5ZHX7 304 33589 Y46 L R D P Q A K Y P L P L V G K
Frog Xenopus laevis Q5PQA4 296 32646 Y38 L L D P N A K Y P L P L I E K
Zebra Danio Brachydanio rerio Q0P487 309 34369 Y51 L Q D P S V K Y P L P L I E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623086 308 34610 Y50 L V D P V V K Y S L P L I K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194747 350 39037 I92 L I D A D T K I P L Q L V Y R
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 I364 L S N P R E K I H C R L V G K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 56.6 37.5 N.A. 82.2 82.6 N.A. 55.3 62.8 60.8 56.3 N.A. N.A. 52.2 N.A. 47.4
Protein Similarity: 100 80.6 57.4 40.8 N.A. 91.3 93.1 N.A. 71 75.6 77.6 68.9 N.A. N.A. 70.1 N.A. 62.5
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. 46.6 73.3 86.6 86.6 N.A. N.A. 66.6 N.A. 40
P-Site Similarity: 100 100 100 86.6 N.A. 100 100 N.A. 66.6 93.3 86.6 86.6 N.A. N.A. 73.3 N.A. 60
Percent
Protein Identity: N.A. 21.2 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 31.5 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 46.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 62 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 93 0 8 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 47 16 0 0 0 0 0 0 0 62 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 16 0 0 0 0 70 0 0 % I
% Lys: 0 0 0 0 0 0 100 0 0 0 0 0 0 8 85 % K
% Leu: 100 16 0 0 0 0 0 0 16 93 0 100 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 16 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 85 0 0 0 0 70 0 77 0 0 0 0 % P
% Gln: 0 54 0 0 8 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 16 0 0 0 16 % R
% Ser: 0 8 0 8 8 0 0 0 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 8 16 0 0 0 0 0 0 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 85 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _