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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R2 All Species: 43.64
Human Site: S74 Identified Species: 80
UniProt: Q6BCY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6BCY4 NP_057313.2 276 31458 S74 R A Y T P V S S D D D R G F V
Chimpanzee Pan troglodytes XP_001166922 336 37776 S134 R A Y T P V S S D D D R G F V
Rhesus Macaque Macaca mulatta XP_001099164 468 51616 S266 R A Y T P V S S D D D R G F V
Dog Lupus familis XP_542485 636 70694 S434 R A Y T P V S S D D D R G F V
Cat Felis silvestris
Mouse Mus musculus Q3KNK3 276 31342 S74 R A Y T P V S S D D D Q G F V
Rat Rattus norvegicus Q6AY12 276 31220 S74 R A Y T P V S S D D D Q G F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518224 300 33346 G98 R P Y T P V T G D E N R G Y V
Chicken Gallus gallus Q5ZHX7 304 33589 S102 R A Y T P V S S D E T K G Y V
Frog Xenopus laevis Q5PQA4 296 32646 S94 R A Y T P V S S D E V K G H V
Zebra Danio Brachydanio rerio Q0P487 309 34369 S107 R A Y T P V S S D Q D Q G Y V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623086 308 34610 S106 R S Y T P V S S D D D H G Y V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194747 350 39037 S148 R P Y T P V T S D E D R G Y V
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 M420 R A Y T P T S M V D E I G H F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 56.6 37.5 N.A. 82.2 82.6 N.A. 55.3 62.8 60.8 56.3 N.A. N.A. 52.2 N.A. 47.4
Protein Similarity: 100 80.6 57.4 40.8 N.A. 91.3 93.1 N.A. 71 75.6 77.6 68.9 N.A. N.A. 70.1 N.A. 62.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 60 73.3 73.3 80 N.A. N.A. 80 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 93.3 86.6 93.3 N.A. N.A. 93.3 N.A. 93.3
Percent
Protein Identity: N.A. 21.2 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 31.5 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 60 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 93 62 70 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 31 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 8 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 16 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 16 0 0 100 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 24 0 0 0 % Q
% Arg: 100 0 0 0 0 0 0 0 0 0 0 47 0 0 0 % R
% Ser: 0 8 0 0 0 0 85 85 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 100 0 8 16 0 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 93 0 0 8 0 8 0 0 0 93 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 100 0 0 0 0 0 0 0 0 0 0 39 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _