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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A4
All Species:
20.91
Human Site:
S644
Identified Species:
38.33
UniProt:
Q6AI14
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI14
NP_001011552.2
798
89816
S644
E
S
M
R
K
G
H
S
L
P
W
G
K
P
A
Chimpanzee
Pan troglodytes
XP_001163482
798
89999
S644
E
S
M
R
K
G
H
S
L
P
W
G
K
P
A
Rhesus Macaque
Macaca mulatta
XP_001108212
798
89826
S644
E
S
M
R
K
G
H
S
L
P
W
G
K
P
A
Dog
Lupus familis
XP_531775
801
90567
S642
E
S
I
R
K
D
S
S
L
N
H
E
R
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE1
797
90919
S644
E
S
M
R
K
G
Q
S
L
P
W
G
K
P
A
Rat
Rattus norvegicus
P26434
717
81504
Y573
S
V
A
S
P
T
P
Y
Q
S
E
R
I
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514658
801
90778
S651
E
S
M
R
K
S
S
S
L
P
W
G
K
S
P
Chicken
Gallus gallus
Q5ZJ75
574
64115
L430
P
Y
A
L
S
L
H
L
G
L
E
P
I
E
K
Frog
Xenopus laevis
NP_001081553
781
87800
Y629
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
Zebra Danio
Brachydanio rerio
NP_001107567
746
85353
A602
L
R
S
G
S
F
H
A
T
N
S
A
N
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
T523
V
R
A
Y
E
K
I
T
L
E
D
A
I
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
G391
L
W
Y
S
G
L
R
G
A
M
A
F
A
L
A
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
K489
M
L
E
V
L
N
I
K
T
G
C
I
S
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
59.2
N.A.
83.4
76.6
N.A.
78.1
23.8
39.4
43.6
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
100
99.6
98.3
73.5
N.A.
89.9
81.1
N.A.
86.7
38.8
57.1
63.5
N.A.
N.A.
N.A.
51.7
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
93.3
0
N.A.
73.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
60
N.A.
93.3
0
N.A.
73.3
6.6
13.3
20
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
0
0
8
8
0
8
16
8
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
47
0
8
0
8
0
0
0
0
8
16
8
0
16
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
8
31
0
8
8
8
0
39
0
0
8
% G
% His:
0
0
0
0
0
0
39
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
16
0
0
0
0
8
24
0
0
% I
% Lys:
0
0
0
0
47
8
0
8
0
0
0
0
39
8
8
% K
% Leu:
16
8
0
8
16
16
0
8
54
8
0
0
8
8
8
% L
% Met:
8
0
39
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
16
0
0
8
0
0
% N
% Pro:
8
0
0
0
8
0
8
0
0
39
0
8
0
31
8
% P
% Gln:
0
0
8
0
0
0
8
0
8
0
0
0
0
8
0
% Q
% Arg:
0
24
0
54
0
8
8
0
0
8
0
8
8
8
0
% R
% Ser:
8
47
8
16
16
8
24
47
0
8
8
0
8
8
8
% S
% Thr:
8
0
0
0
0
8
0
8
16
0
0
8
0
8
0
% T
% Val:
8
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
39
0
0
0
0
% W
% Tyr:
0
8
8
8
0
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _