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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEATR6 All Species: 26.97
Human Site: Y293 Identified Species: 53.94
UniProt: Q6AI08 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI08 NP_071353.4 1181 128781 Y293 Y P T P L P Q Y D G R T P I K
Chimpanzee Pan troglodytes XP_001140673 1181 128587 Y293 Y P T P L P Q Y D G R T P I K
Rhesus Macaque Macaca mulatta XP_001115127 952 103235 K89 P T L N K K K K S K V K P K K
Dog Lupus familis XP_537718 1182 128995 Y294 Y P T P L P Q Y D G R P P V R
Cat Felis silvestris
Mouse Mus musculus Q6P1G0 1184 128904 Y293 Y P T P L P Q Y D G R S P V K
Rat Rattus norvegicus A1EC95 1252 136487 Y364 Y P T P L P Q Y D G R S P V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509279 1130 123255 Y256 Y P A P L P Q Y D G R S P V K
Chicken Gallus gallus XP_415906 1161 126733 Y278 I E M P A A L Y P A P L P Q Y
Frog Xenopus laevis Q7ZY56 1174 130030 Y302 Y P T P L A Q Y D G R S P T K
Zebra Danio Brachydanio rerio A9JRI0 1201 130485 V302 Y G L P G I S V E M P Q V L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569860 940 104465 E77 G R W L V A K E Q L P L L L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195525 1165 129381 W264 R Y M P L V L W R L Q F T P F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 77.9 88.6 N.A. 83.6 78.7 N.A. 70.2 67.5 64 54.4 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 99.3 79.2 93 N.A. 90.1 85.8 N.A. 79.7 78.4 76.5 71.9 N.A. 42 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 80 N.A. 86.6 86.6 N.A. 80 20 80 13.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 93.3 N.A. 100 100 N.A. 93.3 20 86.6 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 25 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 9 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % F
% Gly: 9 9 0 0 9 0 0 0 0 59 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 9 0 0 0 0 0 0 0 17 0 % I
% Lys: 0 0 0 0 9 9 17 9 0 9 0 9 0 9 59 % K
% Leu: 0 0 17 9 67 0 17 0 0 17 0 17 9 17 0 % L
% Met: 0 0 17 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 59 0 84 0 50 0 0 9 0 25 9 75 9 0 % P
% Gln: 0 0 0 0 0 0 59 0 9 0 9 9 0 9 0 % Q
% Arg: 9 9 0 0 0 0 0 0 9 0 59 0 0 0 9 % R
% Ser: 0 0 0 0 0 0 9 0 9 0 0 34 0 0 0 % S
% Thr: 0 9 50 0 0 0 0 0 0 0 0 17 9 9 0 % T
% Val: 0 0 0 0 9 9 0 9 0 0 9 0 9 34 0 % V
% Trp: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 67 9 0 0 0 0 0 67 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _