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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR6
All Species:
25.45
Human Site:
S223
Identified Species:
50.91
UniProt:
Q6AI08
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI08
NP_071353.4
1181
128781
S223
T
I
L
Q
S
P
K
S
S
D
M
D
D
I
T
Chimpanzee
Pan troglodytes
XP_001140673
1181
128587
S223
T
I
L
Q
S
P
K
S
S
D
M
D
D
I
T
Rhesus Macaque
Macaca mulatta
XP_001115127
952
103235
G31
L
T
Q
T
D
E
L
G
A
L
L
A
V
L
K
Dog
Lupus familis
XP_537718
1182
128995
S224
T
T
L
Q
S
P
K
S
S
D
M
D
D
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1G0
1184
128904
S223
T
I
L
Q
S
P
K
S
S
D
M
D
D
I
T
Rat
Rattus norvegicus
A1EC95
1252
136487
S294
T
I
L
Q
S
P
K
S
S
D
M
D
D
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509279
1130
123255
L198
D
I
L
F
C
M
L
L
Q
N
A
M
K
G
I
Chicken
Gallus gallus
XP_415906
1161
126733
T215
S
V
L
Q
S
S
K
T
S
N
V
D
D
I
V
Frog
Xenopus laevis
Q7ZY56
1174
130030
P232
T
V
L
Q
T
P
K
P
N
I
V
D
D
I
A
Zebra Danio
Brachydanio rerio
A9JRI0
1201
130485
S243
I
L
L
R
T
L
Q
S
T
K
P
P
D
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569860
940
104465
R19
N
L
A
G
F
W
P
R
L
S
A
L
T
H
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195525
1165
129381
S205
Q
Q
N
R
L
W
D
S
M
A
L
A
F
D
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
77.9
88.6
N.A.
83.6
78.7
N.A.
70.2
67.5
64
54.4
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
79.2
93
N.A.
90.1
85.8
N.A.
79.7
78.4
76.5
71.9
N.A.
42
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
13.3
53.3
53.3
20
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
100
100
N.A.
20
86.6
80
60
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
9
9
17
17
0
0
17
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
9
0
0
42
0
59
67
9
9
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
42
0
0
0
0
0
0
0
9
0
0
0
59
9
% I
% Lys:
0
0
0
0
0
0
59
0
0
9
0
0
9
0
9
% K
% Leu:
9
17
75
0
9
9
17
9
9
9
17
9
0
9
0
% L
% Met:
0
0
0
0
0
9
0
0
9
0
42
9
0
0
9
% M
% Asn:
9
0
9
0
0
0
0
0
9
17
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
50
9
9
0
0
9
9
0
0
0
% P
% Gln:
9
9
9
59
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
50
9
0
59
50
9
0
0
0
0
0
% S
% Thr:
50
17
0
9
17
0
0
9
9
0
0
0
9
0
42
% T
% Val:
0
17
0
0
0
0
0
0
0
0
17
0
9
9
9
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _