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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR6
All Species:
14.55
Human Site:
S1124
Identified Species:
29.09
UniProt:
Q6AI08
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI08
NP_071353.4
1181
128781
S1124
D
D
T
G
A
P
H
S
P
Q
E
R
D
Q
M
Chimpanzee
Pan troglodytes
XP_001140673
1181
128587
S1124
D
D
T
G
A
P
H
S
P
Q
E
R
D
Q
M
Rhesus Macaque
Macaca mulatta
XP_001115127
952
103235
M902
S
P
Q
E
T
D
Q
M
V
R
M
A
L
K
H
Dog
Lupus familis
XP_537718
1182
128995
N1124
E
D
T
G
A
P
H
N
L
H
E
R
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1G0
1184
128904
T1127
D
D
P
G
A
V
H
T
P
Q
E
R
V
Q
M
Rat
Rattus norvegicus
A1EC95
1252
136487
S1195
D
D
P
G
A
V
H
S
P
Q
E
R
N
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509279
1130
123255
Q1080
G
D
G
L
S
S
P
Q
E
R
G
G
S
L
K
Chicken
Gallus gallus
XP_415906
1161
126733
D1111
N
E
A
G
M
H
T
D
L
C
E
R
E
R
L
Frog
Xenopus laevis
Q7ZY56
1174
130030
Q1124
E
V
Q
G
D
E
S
Q
R
E
H
Q
D
R
G
Zebra Danio
Brachydanio rerio
A9JRI0
1201
130485
G1131
V
P
S
A
G
A
D
G
E
E
A
L
D
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569860
940
104465
T890
R
L
E
E
V
Q
A
T
W
R
R
V
A
F
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195525
1165
129381
T1109
W
L
R
G
L
C
V
T
L
K
E
E
D
N
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
77.9
88.6
N.A.
83.6
78.7
N.A.
70.2
67.5
64
54.4
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
79.2
93
N.A.
90.1
85.8
N.A.
79.7
78.4
76.5
71.9
N.A.
42
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
66.6
N.A.
73.3
80
N.A.
6.6
20
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
80
86.6
N.A.
20
53.3
40
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
42
9
9
0
0
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% C
% Asp:
34
50
0
0
9
9
9
9
0
0
0
0
50
0
0
% D
% Glu:
17
9
9
17
0
9
0
0
17
17
59
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
9
67
9
0
0
9
0
0
9
9
0
0
9
% G
% His:
0
0
0
0
0
9
42
0
0
9
9
0
0
9
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% K
% Leu:
0
17
0
9
9
0
0
0
25
0
0
9
9
9
17
% L
% Met:
0
0
0
0
9
0
0
9
0
0
9
0
0
0
34
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
0
0
9
9
0
% N
% Pro:
0
17
17
0
0
25
9
0
34
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
9
9
17
0
34
0
9
0
42
0
% Q
% Arg:
9
0
9
0
0
0
0
0
9
25
9
50
0
17
9
% R
% Ser:
9
0
9
0
9
9
9
25
0
0
0
0
9
0
9
% S
% Thr:
0
0
25
0
9
0
9
25
0
0
0
0
0
0
0
% T
% Val:
9
9
0
0
9
17
9
0
9
0
0
9
9
0
9
% V
% Trp:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _