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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR6
All Species:
23.94
Human Site:
S1112
Identified Species:
47.88
UniProt:
Q6AI08
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI08
NP_071353.4
1181
128781
S1112
Y
I
L
Q
F
L
K
S
G
A
E
G
D
D
T
Chimpanzee
Pan troglodytes
XP_001140673
1181
128587
S1112
Y
I
L
Q
F
L
K
S
G
A
E
G
D
D
T
Rhesus Macaque
Macaca mulatta
XP_001115127
952
103235
T890
S
G
A
E
G
D
D
T
G
A
P
H
S
P
Q
Dog
Lupus familis
XP_537718
1182
128995
S1112
F
I
L
Q
F
L
K
S
G
T
E
G
E
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1G0
1184
128904
S1115
Y
I
L
Q
F
L
K
S
G
A
E
G
D
D
P
Rat
Rattus norvegicus
A1EC95
1252
136487
S1183
Y
I
L
Q
F
L
K
S
G
A
G
G
D
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509279
1130
123255
K1068
A
Y
V
L
Q
H
L
K
P
G
A
E
G
D
G
Chicken
Gallus gallus
XP_415906
1161
126733
S1099
Y
V
V
Q
Y
M
K
S
G
V
E
D
N
E
A
Frog
Xenopus laevis
Q7ZY56
1174
130030
H1112
S
I
R
N
Y
V
L
H
Y
V
K
S
E
V
Q
Zebra Danio
Brachydanio rerio
A9JRI0
1201
130485
R1119
A
L
L
I
S
H
L
R
D
E
G
L
V
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569860
940
104465
S878
D
L
P
M
M
R
E
S
L
E
E
D
R
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195525
1165
129381
S1097
E
F
L
I
R
K
A
S
F
L
E
E
W
L
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
77.9
88.6
N.A.
83.6
78.7
N.A.
70.2
67.5
64
54.4
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
79.2
93
N.A.
90.1
85.8
N.A.
79.7
78.4
76.5
71.9
N.A.
42
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
93.3
86.6
N.A.
6.6
40
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
86.6
N.A.
13.3
80
33.3
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
9
0
0
42
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
9
0
9
0
0
17
34
50
0
% D
% Glu:
9
0
0
9
0
0
9
0
0
17
59
17
17
9
9
% E
% Phe:
9
9
0
0
42
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
9
0
0
0
59
9
17
42
9
0
9
% G
% His:
0
0
0
0
0
17
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
50
0
17
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
50
9
0
0
9
0
0
0
0
% K
% Leu:
0
17
59
9
0
42
25
0
9
9
0
9
0
17
0
% L
% Met:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
9
0
9
0
0
17
17
% P
% Gln:
0
0
0
50
9
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
9
0
9
9
0
9
0
0
0
0
9
0
9
% R
% Ser:
17
0
0
0
9
0
0
67
0
0
0
9
9
0
9
% S
% Thr:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
25
% T
% Val:
0
9
17
0
0
9
0
0
0
17
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
42
9
0
0
17
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _