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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYTSA
All Species:
31.21
Human Site:
Y477
Identified Species:
62.42
UniProt:
Q69YQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q69YQ0
NP_056145.2
1117
124592
Y477
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
K
Chimpanzee
Pan troglodytes
Q2KNA1
1117
124542
Y477
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
K
Rhesus Macaque
Macaca mulatta
XP_001094607
1117
124500
Y477
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
K
Dog
Lupus familis
XP_546643
1059
117905
L464
D
I
Q
E
G
K
I
L
E
L
E
Q
K
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q2KN98
1118
124469
Y478
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
K
Rat
Rattus norvegicus
Q2KN99
1118
124320
Y478
L
D
E
H
H
I
S
Y
V
I
D
E
D
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509479
1058
116948
E462
S
Q
D
E
K
V
L
E
L
E
H
K
C
T
E
Chicken
Gallus gallus
Q2KN97
1118
124891
Y478
L
D
E
H
H
I
S
Y
V
I
D
E
D
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2KN93
1132
123609
Y468
L
D
E
H
G
V
A
Y
S
V
D
E
D
I
K
Tiger Blowfish
Takifugu rubipres
Q2KN94
1118
123301
Y466
L
D
E
H
H
V
S
Y
V
L
E
E
D
I
K
Fruit Fly
Dros. melanogaster
NP_001036254
1094
121635
P472
L
L
R
D
T
K
Q
P
A
P
E
V
S
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788398
902
102086
L313
I
T
V
F
K
G
K
L
S
S
L
E
V
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
39.6
N.A.
95.1
94.7
N.A.
40.8
91
N.A.
66.9
73.7
27.1
N.A.
N.A.
23.9
Protein Similarity:
100
99.8
99.7
58.7
N.A.
97.1
96.6
N.A.
59.3
95
N.A.
78.1
83.2
46.5
N.A.
N.A.
42.3
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
93.3
N.A.
60
73.3
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
33.3
100
N.A.
86.6
100
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% C
% Asp:
9
67
9
9
0
0
0
0
0
0
59
0
67
0
0
% D
% Glu:
0
0
67
17
0
0
0
9
9
9
25
75
0
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
67
59
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
9
0
0
0
50
9
0
0
50
0
0
0
17
0
% I
% Lys:
0
0
0
0
17
17
9
0
0
0
0
9
9
0
67
% K
% Leu:
75
9
0
0
0
0
9
17
9
17
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
9
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
9
0
0
0
0
0
59
0
17
9
0
0
9
0
9
% S
% Thr:
0
9
0
0
9
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
9
0
0
25
0
0
59
9
0
9
9
42
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _