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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX8
All Species:
20.3
Human Site:
Y116
Identified Species:
40.61
UniProt:
Q68G74
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68G74
NP_001001933.1
356
39273
Y116
L
G
R
H
T
S
C
Y
I
K
D
K
D
I
F
Chimpanzee
Pan troglodytes
XP_001135172
363
40012
E116
S
C
Y
I
K
N
K
E
I
F
C
K
M
D
Y
Rhesus Macaque
Macaca mulatta
XP_001097664
553
60695
Y313
L
G
R
H
T
S
C
Y
I
K
D
K
D
I
F
Dog
Lupus familis
XP_547330
377
41693
Y137
L
G
R
H
T
S
C
Y
I
K
D
K
D
I
F
Cat
Felis silvestris
Mouse
Mus musculus
O35652
367
40678
Y137
L
G
R
H
T
S
C
Y
I
K
D
K
D
I
F
Rat
Rattus norvegicus
Q80W90
388
42915
S132
A
R
C
H
L
G
I
S
A
S
E
M
V
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521123
673
74019
Y317
L
G
R
H
T
S
C
Y
I
K
D
K
D
I
F
Chicken
Gallus gallus
Q90881
397
44091
G139
R
C
A
R
C
H
L
G
I
S
A
S
E
M
V
Frog
Xenopus laevis
NP_001079958
282
31597
A59
V
Q
G
S
P
G
A
A
M
D
E
D
S
C
S
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
G139
R
C
A
R
C
H
L
G
I
S
A
S
E
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
E52
Q
Q
S
C
F
I
R
E
R
Q
V
Y
C
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785118
357
38596
Y119
N
V
F
C
R
K
C
Y
S
R
E
F
G
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.4
64.1
87.5
N.A.
88.5
30.4
N.A.
50.6
29.9
57
30.8
N.A.
34.5
N.A.
N.A.
38.6
Protein Similarity:
100
69.6
64.1
89.3
N.A.
89.9
50.2
N.A.
51.4
49.8
62.6
50
N.A.
48
N.A.
N.A.
56.3
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
100
6.6
0
6.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
20
N.A.
100
20
20
20
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
0
0
9
9
9
0
17
0
0
0
9
% A
% Cys:
0
25
9
17
17
0
50
0
0
0
9
0
9
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
42
9
42
9
0
% D
% Glu:
0
0
0
0
0
0
0
17
0
0
25
0
17
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
9
0
9
0
0
42
% F
% Gly:
0
42
9
0
0
17
0
17
0
0
0
0
9
0
0
% G
% His:
0
0
0
50
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
9
0
67
0
0
0
0
42
0
% I
% Lys:
0
0
0
0
9
9
9
0
0
42
0
50
0
9
9
% K
% Leu:
42
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
9
9
25
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
17
9
42
17
9
0
9
0
9
9
0
0
0
0
9
% R
% Ser:
9
0
9
9
0
42
0
9
9
25
0
17
9
0
9
% S
% Thr:
0
0
0
0
42
0
0
0
0
0
0
0
0
9
0
% T
% Val:
9
9
0
0
0
0
0
0
0
0
9
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
50
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _