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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHX8 All Species: 22.73
Human Site: S57 Identified Species: 45.45
UniProt: Q68G74 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68G74 NP_001001933.1 356 39273 S57 S A P L S P S S S P R S M A S
Chimpanzee Pan troglodytes XP_001135172 363 40012 S57 P S V C S P P S A A S S V P S
Rhesus Macaque Macaca mulatta XP_001097664 553 60695 S254 S A P L S P S S S P R S M A S
Dog Lupus familis XP_547330 377 41693 S78 S A P L S P S S S P R S M A S
Cat Felis silvestris
Mouse Mus musculus O35652 367 40678 S78 S G P L S P S S S P Q S M A S
Rat Rattus norvegicus Q80W90 388 42915 Y73 G G K I S D R Y Y L L A V D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521123 673 74019 S258 S A P L S P S S S P R S M A S
Chicken Gallus gallus Q90881 397 44091 D80 G C G G K I S D R Y Y L L A V
Frog Xenopus laevis NP_001079958 282 31597
Zebra Danio Brachydanio rerio Q1LWV4 396 44002 D80 G C G G K I S D R Y Y L L A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRC7 275 31013
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785118 357 38596 S60 K P I D T T E S K S E S C A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.4 64.1 87.5 N.A. 88.5 30.4 N.A. 50.6 29.9 57 30.8 N.A. 34.5 N.A. N.A. 38.6
Protein Similarity: 100 69.6 64.1 89.3 N.A. 89.9 50.2 N.A. 51.4 49.8 62.6 50 N.A. 48 N.A. N.A. 56.3
P-Site Identity: 100 33.3 100 100 N.A. 86.6 6.6 N.A. 100 13.3 0 13.3 N.A. 0 N.A. N.A. 20
P-Site Similarity: 100 53.3 100 100 N.A. 93.3 26.6 N.A. 100 20 0 20 N.A. 0 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 0 0 0 0 0 9 9 0 9 0 67 0 % A
% Cys: 0 17 0 9 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 9 0 9 0 17 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 25 17 17 17 0 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 17 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 9 0 17 0 0 0 9 0 0 0 0 0 9 % K
% Leu: 0 0 0 42 0 0 0 0 0 9 9 17 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 42 0 0 50 9 0 0 42 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 17 0 34 0 0 0 0 % R
% Ser: 42 9 0 0 59 0 59 59 42 9 9 59 0 0 50 % S
% Thr: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 0 17 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 9 17 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _