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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STEAP4
All Species:
29.7
Human Site:
Y192
Identified Species:
72.59
UniProt:
Q687X5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q687X5
NP_078912.2
459
51981
Y192
A
A
K
E
I
E
K
Y
P
L
Q
L
F
P
M
Chimpanzee
Pan troglodytes
XP_527809
459
51993
Y192
A
A
K
E
I
E
K
Y
P
L
Q
L
F
P
M
Rhesus Macaque
Macaca mulatta
XP_001104041
459
52019
Y192
A
A
K
E
I
E
K
Y
P
L
Q
L
F
P
M
Dog
Lupus familis
XP_539406
782
85782
Y366
A
A
K
E
I
E
N
Y
P
L
Q
L
F
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q923B6
470
52976
Y192
A
A
S
E
I
E
N
Y
P
L
Q
L
F
P
M
Rat
Rattus norvegicus
Q4V8K1
470
52746
Y192
A
A
K
E
I
E
N
Y
P
L
Q
L
F
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509103
487
55002
Y207
A
A
K
E
I
E
D
Y
P
L
Q
L
F
P
M
Chicken
Gallus gallus
XP_001235257
440
49633
K193
L
Q
L
F
P
M
W
K
I
P
I
F
L
S
L
Frog
Xenopus laevis
NP_001083283
458
51981
Y191
A
A
N
E
V
E
N
Y
P
L
Q
L
F
P
M
Zebra Danio
Brachydanio rerio
NP_001017734
464
52110
L194
Q
L
F
P
L
W
R
L
P
F
Y
I
A
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
51.5
N.A.
80.4
79.5
N.A.
72.4
63.6
69.9
59.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.6
54.9
N.A.
87.8
88.7
N.A.
82.5
75.8
83.8
76
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
93.3
0
80
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
93.3
6.6
86.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
80
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
80
0
80
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
0
0
0
0
10
0
10
80
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
70
0
0
0
10
0
10
10
0
10
0
% I
% Lys:
0
0
60
0
0
0
30
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
0
10
0
0
10
0
80
0
80
10
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
80
% M
% Asn:
0
0
10
0
0
0
40
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
0
90
10
0
0
0
80
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
80
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _