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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CEP135
All Species:
13.03
Human Site:
T488
Identified Species:
23.89
UniProt:
Q66GS9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q66GS9
NP_079285.2
1140
133504
T488
E
K
S
S
I
F
R
T
P
E
K
G
D
Y
N
Chimpanzee
Pan troglodytes
XP_517281
1140
133474
T488
E
K
S
S
I
F
R
T
P
E
K
G
D
Y
N
Rhesus Macaque
Macaca mulatta
XP_001084949
1131
132474
T488
E
K
N
S
I
F
R
T
P
E
K
G
D
Y
N
Dog
Lupus familis
XP_539276
919
107911
S333
L
H
A
L
R
Q
E
S
A
Q
T
T
V
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D4
1140
133327
C488
E
K
P
P
V
V
K
C
S
E
K
G
D
C
S
Rat
Rattus norvegicus
Q9Z220
712
82993
L126
R
D
S
L
R
E
R
L
K
I
A
Q
A
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518640
1143
132891
A492
E
L
E
D
T
F
L
A
P
S
E
P
K
S
D
Chicken
Gallus gallus
O42184
1433
161009
S676
L
K
Q
E
N
E
K
S
Q
H
L
K
E
I
E
Frog
Xenopus laevis
P85120
2058
236320
V650
N
E
I
L
T
K
K
V
T
S
I
K
I
V
E
Zebra Danio
Brachydanio rerio
Q5RG45
1164
134937
G495
G
R
S
P
R
G
R
G
S
W
H
G
K
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648749
1059
123068
S456
F
L
H
A
Q
I
K
S
K
D
E
E
L
K
A
Honey Bee
Apis mellifera
XP_001121524
648
75877
K62
Q
S
T
I
D
P
Y
K
C
D
N
V
R
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781904
1062
122717
R467
K
D
V
T
S
S
F
R
D
L
S
I
A
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
93.5
71.8
N.A.
82.8
21.6
N.A.
69
20.2
20.9
51.6
N.A.
21.9
24.4
N.A.
28.1
Protein Similarity:
100
100
95.7
77.1
N.A.
92.8
40
N.A.
85
40.2
36.3
73.9
N.A.
45.1
38.5
N.A.
52.6
P-Site Identity:
100
100
93.3
0
N.A.
40
20
N.A.
20
6.6
0
20
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
60
26.6
N.A.
33.3
26.6
13.3
33.3
N.A.
33.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
8
8
0
8
0
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% C
% Asp:
0
16
0
8
8
0
0
0
8
16
0
0
31
8
16
% D
% Glu:
39
8
8
8
0
16
8
0
0
31
16
8
8
0
24
% E
% Phe:
8
0
0
0
0
31
8
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
8
0
8
0
0
0
39
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
8
8
0
0
0
8
% H
% Ile:
0
0
8
8
24
8
0
0
0
8
8
8
8
8
0
% I
% Lys:
8
39
0
0
0
8
31
8
16
0
31
16
16
8
0
% K
% Leu:
16
16
0
24
0
0
8
8
0
8
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
8
0
0
0
31
% N
% Pro:
0
0
8
16
0
8
0
0
31
0
0
8
0
0
0
% P
% Gln:
8
0
8
0
8
8
0
0
8
8
0
8
0
0
0
% Q
% Arg:
8
8
0
0
24
0
39
8
0
0
0
0
8
8
0
% R
% Ser:
0
8
31
24
8
8
0
24
16
16
8
0
0
16
8
% S
% Thr:
0
0
8
8
16
0
0
24
8
0
8
8
0
0
0
% T
% Val:
0
0
8
0
8
8
0
8
0
0
0
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _