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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM91A1
All Species:
41.82
Human Site:
S574
Identified Species:
76.67
UniProt:
Q658Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q658Y4
NP_659400.2
838
93909
S574
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Chimpanzee
Pan troglodytes
XP_519942
838
93965
S574
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Rhesus Macaque
Macaca mulatta
XP_001101343
838
93932
S574
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Dog
Lupus familis
XP_539156
1163
128832
S899
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVG3
837
93445
S574
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Rat
Rattus norvegicus
NP_001121050
838
93556
S574
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511681
888
99764
S623
F
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Chicken
Gallus gallus
XP_001233960
843
94407
S575
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6TEP1
831
93030
S570
Y
D
R
L
L
I
T
S
W
G
H
D
P
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648453
928
103906
E651
D
A
Y
V
L
N
S
E
N
F
R
S
L
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493619
816
91325
T569
P
H
G
T
R
L
T
T
L
P
R
V
L
Q
S
Sea Urchin
Strong. purpuratus
XP_793091
827
93144
T577
Y
D
R
L
L
I
T
T
W
G
H
D
P
G
L
Poplar Tree
Populus trichocarpa
XP_002301074
548
61183
I309
L
G
W
A
D
K
L
I
D
P
G
S
I
L
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
69.5
N.A.
94.9
94.6
N.A.
84.8
88.1
N.A.
78.2
N.A.
36.7
N.A.
43.5
60.8
Protein Similarity:
100
99.8
99.1
71
N.A.
97.3
97.1
N.A.
90.1
93.7
N.A.
87.1
N.A.
54
N.A.
61.9
75.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
N.A.
100
N.A.
6.6
N.A.
6.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
20
N.A.
20
100
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
77
0
0
8
0
0
0
8
0
0
77
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
77
8
0
0
77
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
77
0
0
0
0
% H
% Ile:
0
0
0
0
0
77
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
77
85
8
8
0
8
0
0
0
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
16
0
0
77
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
77
0
8
0
0
0
0
0
16
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
70
0
0
0
16
0
0
16
% S
% Thr:
0
0
0
8
0
0
85
16
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
70
% V
% Trp:
0
0
8
0
0
0
0
0
77
0
0
0
0
0
0
% W
% Tyr:
70
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _